H3c15 Gene Summary [Mouse]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. [provided by RefSeq, Aug 2015]

Details

Type
Protein Coding
Official Symbol
H3c15
Official Name
H3 clustered histone 15 [Source:MGI Symbol;Acc:MGI:2448357]
Ensembl ID
ENSMUSG00000081058
Bio databases IDs NCBI: 97114 Ensembl: ENSMUSG00000081058
Aliases H3 clustered histone 15
Synonyms H3.2-614, H3-614, H3c13, H3c14, H3c2, H3c3, H3c4, H3c6, H3c7, H3 clustered histone 15, Hist2h3c2, Hist2h3c2-ps, Hist2h3ca1, Histone 3.2, histone cluster 2 H3 family member C2, Histone h3 (h3.2)
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse H3c15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • histone fold domain (HFD) superfamily
  • Core histone H2A/H2B/H3/H4
  • Histone H3

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • phosphate
  • propofol
  • PAK2
  • valproic acid
  • L-triiodothyronine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleosomes
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

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