Zfp748 Gene Summary [Mouse]

Enables protein-macromolecule adaptor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in gonad; liver; and mesonephros. [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zfp748
Official Name
zinc finger protein 748 [Source:MGI Symbol;Acc:MGI:1916455]
Ensembl ID
ENSMUSG00000095432
Bio databases IDs NCBI: 212276 Ensembl: ENSMUSG00000095432
Aliases zinc finger protein 748
Synonyms KRAB-O, mszf54, Rslcan20/21, Zfp208, zinc finger protein 748
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp748 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • krueppel associated box
  • transcription regulator
  • Zinc-finger double domain
  • protein binding activity, bridging
  • KRAB (Kruppel-associated box) domain -A box

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • DNA promoter
  • DNA endogenous promoter
  • RNA polymerase II

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus