Ace3 Gene Summary [Mouse]
Predicted to enable metallopeptidase activity and peptidyl-dipeptidase activity. Predicted to be involved in positive regulation of systemic arterial blood pressure and regulation of systemic arterial blood pressure by renin-angiotensin. Located in acrosomal vesicle. Orthologous to human ACE3P (angiotensin I converting enzyme 3, pseudogene). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ace3 |
| Official Name | angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 [Source:MGI Symbol;Acc:MGI:3644400] |
| Ensembl ID | ENSMUSG00000101605 |
| Bio databases IDs | |
| Aliases | angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 |
| Synonyms | angiotensin I converting enzyme 3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, EG217246, RGD1561299 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ace3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Angiotensin-converting enzyme
- protein binding
- peptidase GluZincin family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- acrosome