Marc1 Gene Summary [Rat]
Enables molybdenum ion binding activity; molybdopterin cofactor binding activity; and oxidoreductase activity, acting on other nitrogenous compounds as donors. Contributes to nitrite reductase (NO-forming) activity. Involved in cellular detoxification of nitrogen compound; nitrate metabolic process; and nitric oxide biosynthetic process. Located in mitochondrion. Part of nitric-oxide synthase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | Marc1 |
| Official Name | mitochondrial amidoxime reducing component 1 [Source:RGD Symbol;Acc:1592219] |
| Ensembl ID | ENSRNOG00000004101 |
| Bio databases IDs | |
| Aliases | mitochondrial amidoxime reducing component 1 |
| Synonyms | LOC101930644, MARC1, mitochondrial amidoxime reducing component 1, MOSC1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Marc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- nitrite reductase
- MOSC domain
- molybdenum ion binding
- binding protein
- nitrate reductase
- MOSC N-terminal beta barrel domain
- enzyme
- protein binding
- nitrogenous compound oxidoreductase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Marc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- detoxification of nitrogen compound
- nitric oxide biosynthetic process
- nitrate metabolic process
- cellular detoxification of nitrogen compound
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- pyridoxal phosphate binding
- protein binding
- nitrite reductase (NO-forming) activity
- molybdenum ion binding
- nitrate reductase activity
- oxidoreductase activity, acting on other nitrogenous compounds as donors
- molybdopterin cofactor binding