Fam149b1 Gene Summary [Rat]
Predicted to be involved in cilium assembly and protein localization to cilium. Predicted to be located in cilium. Human ortholog(s) of this gene implicated in Joubert syndrome. Orthologous to human FAM149B1 (family with sequence similarity 149 member B1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam149b1 |
| Official Name | family with sequence similarity 149, member B1 [Source:RGD Symbol;Acc:1359592] |
| Ensembl ID | ENSRNOG00000006554 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 149, member B1 |
| Synonyms | AA536717, AI428773, Fam149b, family with sequence similarity 149, member B, family with sequence similarity 149 member B1, family with sequence similarity 149, member B1, JBTS36, KIAA0974, mKIAA0974, RGD1359592 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fam149b1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Protein of unknown function (DUF3719)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fam149b1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
Cellular Component
Where in the cell the gene product is active
- cilium
Molecular Function
What the gene product does at the molecular level
- protein binding