Crocc

Predicted to enable actin binding activity; kinesin binding activity; and structural molecule activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in several processes, including centriole-centriole cohesion; positive regulation of cilium assembly; and positive regulation of protein localization to cilium. Predicted to act upstream of or within several processes, including ciliary basal body organization; epithelial structure maintenance; and photoreceptor cell maintenance. Predicted to be located in several cellular components, including cytoskeleton; photoreceptor inner segment; and subapical part of cell. Predicted to be active in centriole and centrosome. Orthologous to human CROCC (ciliary rootlet coiled-coil, rootletin). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Crocc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Crocc gene, providing context for its role in the cell.