Spem1 Gene Summary [Rat]

Predicted to be involved in flagellated sperm motility and sperm individualization. Predicted to act upstream of or within spermatogenesis. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human SPEM1 (spermatid maturation 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Spem1
Official Name
spermatid maturation 1 [Source:RGD Symbol;Acc:1593311]
Ensembl ID
ENSRNOG00000015419
Bio databases IDs NCBI: 691981 Ensembl: ENSRNOG00000015419
Aliases spermatid maturation 1
Synonyms 1700095G12Rik, C17orf83, LOC687654, spermatid maturation 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Spem1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • teratozoospermia
  • nonobstructive azoospermia
  • asthenozoospermia
regulated by
role in cell
  • motility
  • individualization
  • removal
  • deformation
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytoplasmic droplets

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Spem1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sperm individualization
  • sperm motility

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • membrane

Gene-Specific Assays for Results You Can Trust

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