Wfdc1 Gene Summary [Rat]
Predicted to enable serine-type endopeptidase inhibitor activity. Involved in several processes, including negative regulation of epithelial cell proliferation; regulation of cell growth; and response to estradiol. Located in extracellular space. Orthologous to human WFDC1 (WAP four-disulfide core domain 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wfdc1 |
| Official Name | WAP four-disulfide core domain 1 [Source:RGD Symbol;Acc:68938] |
| Ensembl ID | ENSRNOG00000015904 |
| Bio databases IDs | |
| Aliases | WAP four-disulfide core domain 1 |
| Synonyms | 2310058A03Rik, LOC105376777, PS20, WAP four-disulfide core domain 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Wfdc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of wound healing
- regulation of cell growth
- negative regulation of cell growth
- negative regulation of inflammatory response
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase inhibitor activity