Lamtor1 Gene Summary [Rat]
Predicted to enable GTPase binding activity and protein-membrane adaptor activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in several processes, including cholesterol homeostasis; positive regulation of intracellular signal transduction; and regulation of cholesterol transport. Located in late endosome membrane and membrane raft. Orthologous to human LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lamtor1 |
| Official Name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 [Source:RGD Symbol;Acc:735078] |
| Ensembl ID | ENSRNOG00000020016 |
| Bio databases IDs | |
| Aliases | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 |
| Synonyms | AABR07038019.1, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 like 1 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lamtor1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Late endosomal/lysosomal adaptor and MAPK and MTOR activator
- guanyl-nucleotide exchange factor
- protein binding activity, bridging
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- lysosome
- lysosome membrane
- endosomal membrane
- membrane rafts