Fbxw12 Gene Summary [Rat]

Predicted to be active in cytoplasm. Orthologous to human FBXW12 (F-box and WD repeat domain containing 12). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fbxw12
Official Name
F-box and WD repeat domain containing 12 [Source:RGD Symbol;Acc:1307859]
Ensembl ID
ENSRNOG00000020720
Bio databases IDs NCBI: 301015 Ensembl: ENSRNOG00000020720
Aliases F-box and WD repeat domain containing 12
Synonyms F-box and WD repeat domain containing 12, FBW12, FBXO12, FBXO35, RGD1307859
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fbxw12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • F-box domain
  • F-box domain superfamily
  • F-box-like
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • epithelial cancer
  • renal cancer
  • obsessive-compulsive disorder
  • kidney carcinoma
regulates
  • PRKN

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Fbxw12 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein ubiquitination

Cellular Component

Where in the cell the gene product is active
  • cytosol

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.