Nckap5 Gene Summary [Rat]

Predicted to be involved in microtubule bundle formation and microtubule depolymerization. Predicted to be active in microtubule plus-end. Used to study proteinuria. Orthologous to human NCKAP5 (NCK associated protein 5). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nckap5
Official Name
NCK-associated protein 5 [Source:RGD Symbol;Acc:1564507]
Ensembl ID
ENSRNOG00000021553
Bio databases IDs NCBI: 363974 Ensembl: ENSRNOG00000021553
Aliases NCK-associated protein 5
Synonyms 8430408F21, D130011D22Rik, E030049G20Rik, ERIH1, ERIH2, FLJ34870, Gm1548, LOC108353717, LOC380609, NAP5, NCK-associated protein 5, RGD1564507
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nckap5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Coiled-coil region of CCDC155 or KASH
  • Family of unknown function (DUF5585)
  • protein binding
  • Nck-associated protein 5, Peripheral clock protein

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • prostate cancer
  • attention deficit hyperactivity disorder
  • metabolic syndrome X
  • hypersomnia
  • IgA deficiency
  • multiple sclerosis
  • bladder exstrophy
  • atopic dermatitis
  • aneurysm
  • spontaneous preterm birth
regulated by
  • topotecan

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nckap5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • microtubule bundle formation
  • microtubule depolymerization

Cellular Component

Where in the cell the gene product is active
  • microtubule plus end

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.