Sp100 Gene Summary [Rat]
Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; chromo shadow domain binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including innate immune response; regulation of DNA-templated transcription; and regulation of signal transduction. Predicted to be located in cytoplasm and nuclear lumen. Predicted to be part of Mre11 complex. Predicted to be active in nucleus. Orthologous to human SP100 (SP100 nuclear antigen). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sp100 |
| Official Name | SP100 nuclear antigen [Source:RGD Symbol;Acc:1359550] |
| Ensembl ID | ENSRNOG00000022769 |
| Bio databases IDs | |
| Aliases | SP100 nuclear antigen |
| Synonyms | LOC100912308, LOC103690030, SP100 nuclear antigen |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sp100 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein dimerization
- PHD zinc finger
- transcription regulator
- transcription factor binding
- protein domain specific binding
- Bromodomain
- identical protein binding
- HSR domain
- RNA polymerase II transcription factor activity, sequence-specific DNA binding
- kinase binding
- protein homodimerization
- PHD finger superfamily
- SAND domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
- nucleoli
- nuclear bodies
- PML nuclear bodies