Fundc2 Gene Summary [Rat]
Predicted to enable phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in autophagy of mitochondrion; intracellular triglyceride homeostasis; and regulation of platelet activation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial outer membrane. Orthologous to human FUNDC2 (FUN14 domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fundc2 |
| Official Name | FUN14 domain containing 2 [Source:RGD Symbol;Acc:1560916] |
| Ensembl ID | ENSRNOG00000024066 |
| Bio databases IDs | |
| Aliases | FUN14 domain containing 2 |
| Synonyms | FUN14 domain containing 2, RGD1560916 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fundc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphatidylinositol-3,4,5-triphosphate binding
- FUN14 family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria