Hbe1 Gene Summary [Rat]
Enables hemoglobin alpha binding activity. Predicted to be involved in hydrogen peroxide catabolic process and oxygen transport. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Part of hemoglobin complex. Human ortholog(s) of this gene implicated in sickle cell anemia. Orthologous to human HBE1 (hemoglobin subunit epsilon 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hbe1 |
| Official Name | hemoglobin subunit epsilon 1 [Source:RGD Symbol;Acc:1305115] |
| Ensembl ID | ENSRNOG00000029286 |
| Bio databases IDs | |
| Aliases | hemoglobin subunit epsilon 1 |
| Synonyms | Glnb1, haemoglobin subunit epsilon 1, haemoglobin subunit ε 1, Hbb-y, hemoglobin subunit epsilon 1, hemoglobin subunit ε 1 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hbe1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Globin
- binding protein
- Globin-like protein superfamily
- hemoglobin binding
Pathways
Biological processes and signaling networks where the Hbe1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown