Defb3 Gene Summary [Rat]
Predicted to enable CCR6 chemokine receptor binding activity; chemoattractant activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in cell chemotaxis and defense response to other organism. Predicted to be active in extracellular space. Orthologous to human DEFB4A (defensin beta 4A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Defb3 |
| Official Name | beta-defensin 3 [Source:RGD Symbol;Acc:1589572] |
| Ensembl ID | ENSRNOG00000038126 |
| Bio databases IDs | |
| Aliases | beta-defensin 3 |
| Synonyms | beta-defensin 3, β-defensin 3 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Defb3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Beta defensin
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space