Fpr2 Gene Summary [Rat]
Enables RAGE receptor binding activity. Involved in dentinogenesis. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Biomarker of dentin caries. Orthologous to human FPR2 (formyl peptide receptor 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fpr2 |
| Official Name | formyl peptide receptor 2 [Source:RGD Symbol;Acc:1584013] |
| Ensembl ID | ENSRNOG00000042605 |
| Bio databases IDs | |
| Aliases | formyl peptide receptor 2 |
| Synonyms | Alx, Alxr, formyl peptide receptor 2, Fpr2l, Fprl1, Fpr-rs2, LOC100363653, LOC681693, Lxa4r |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fpr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Cholecystokinin A receptor, N-terminal
- signaling receptor activity
- scavenger receptor binding
- N-formyl peptide receptor
- 7 transmembrane receptor (rhodopsin family)
- receptor binding
- beta-amyloid binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Fpr2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- AGER
- Trp-Lys-Tyr-Met-Val-D-Met
disease
- experimental autoimmune neuritis
- endometriosis
regulated by
- progesterone
- Trp-Lys-Tyr-Met-Val-D-Met
role in cell
- proliferation
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm