Cfc1 Gene Summary [Rat]
Predicted to enable activin receptor binding activity and nodal binding activity. Involved in female pregnancy. Predicted to be active in cell surface and extracellular region. Human ortholog(s) of this gene implicated in tetralogy of Fallot; visceral heterotaxy; and visceral heterotaxy 2. Orthologous to several human genes including CFC1B (cryptic, EGF-CFC family member 1B). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cfc1 |
| Official Name | cripto, FRL-1, cryptic family 1 [Source:RGD Symbol;Acc:1562188] |
| Ensembl ID | ENSRNOG00000042646 |
| Bio databases IDs | |
| Aliases | cripto, FRL-1, cryptic family 1 |
| Synonyms | cripto, FRL-1, cryptic family 1, RGD1562188 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cfc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cripto_Frl-1_Cryptic (CFC)
- receptor binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown