Trappc2b Gene Summary [Rat]
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment and perinuclear region of cytoplasm. Predicted to be part of TRAPP complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in X-linked spondyloepiphyseal dysplasia tarda. Orthologous to human TRAPPC2 (trafficking protein particle complex subunit 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Trappc2b |
| Official Name | trafficking protein particle complex 2B [Source:RGD Symbol;Acc:6499350] |
| Ensembl ID | ENSRNOG00000049062 |
| Bio databases IDs | |
| Aliases | trafficking protein particle complex 2B |
| Synonyms | 0610009B22Rik, LOC287274, trafficking protein particle complex 2B |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Trappc2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ion channel binding
- transcription factor binding
- Sedlin, N-terminal conserved region
- Longin-like domains
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- perinuclear region
- Endoplasmic Reticulum
- nucleoplasm
- outer nuclear membrane