Nccrp1 Gene Summary [Rat]
Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in positive regulation of cell population proliferation and protein catabolic process. Predicted to be located in cytosol. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human NCCRP1 (NCCRP1, F-box associated domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nccrp1 |
| Official Name | NCCRP1, F-box associated domain containing [Source:RGD Symbol;Acc:1305932] |
| Ensembl ID | ENSRNOG00000054506 |
| Bio databases IDs | |
| Aliases | NCCRP1, F-box associated domain containing |
| Synonyms | 1190020J12Rik, FBXO50, Gm163, NCCRP1, F-box associated domain containing, non-specific cytotoxic cell receptor protein 1 homolog (zebrafish), RGD1305932 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nccrp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- F-box associated region
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Nccrp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycoprotein catabolic process
- positive regulation of cell proliferation
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
- cytosol
- SCF ubiquitin ligase complex
Molecular Function
What the gene product does at the molecular level
- protein binding