Usp9y

Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cell migration and regulation of protein stability. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in Y-linked spermatogenic failure 2; female-restricted syndromic X-linked intellectual disability 99; and non-syndromic X-linked intellectual disability 99. Orthologous to several human genes including USP9Y (ubiquitin specific peptidase 9 Y-linked). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Usp9y often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Usp9y gene in rat plays a role, providing insight into its function and relevance in health or disease.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.