Tbc1d22b Gene Summary [Rat]

Predicted to enable 14-3-3 protein binding activity and GTPase activator activity. Predicted to be active in Golgi apparatus. Orthologous to human TBC1D22B (TBC1 domain family member 22B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tbc1d22b
Official Name
TBC1 domain family, member 22B [Source:RGD Symbol;Acc:1564987]
Ensembl ID
ENSRNOG00000059458
Bio databases IDs NCBI: 502414 Ensembl: ENSRNOG00000059458
Aliases TBC1 domain family, member 22B
Synonyms C6orf197, TBC1 domain family member 22B, TBC1 domain family, member 22B
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tbc1d22b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Rab-GTPase-TBC domain
  • Domain in Tre-2, BUB2p, and Cdc16p
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • acne
regulated by
  • indomethacin
  • collagen-related peptide
  • mir-122 (includes others)
  • Bacillus anthracis Sterne strain 7702
  • eptifibatide
role in cell
  • formation
  • exocytosis by
  • exocytosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tbc1d22b gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • GTPase activator activity
  • 14-3-3 protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.