qBiomarker™ Somatic Mutation PCR Array Human APC/CTNNB1 (beta-catenin) Pathway
GeneGlobe ID: SMH-010AA | Cat. No.: 337021 | qBiomarker Somatic Mutation PCR Arrays
Product Specification
PCR plate and master mix
Target List
APC
The most commonly detected APC inactivation mutations are mainly composed of truncation mutations (due to nonsense mutations and frameshift mutations) and point mutations between codons 1250 and 1578.
CDH1
The most important CDH1 mutations are either missense mutations or frameshift mutations that lead to C-terminal truncation and secreted E-cadherin fragments.
CTNNB1
The most frequently detected CTNNB1 mutations result in abnormal WNT signaling activity. The mutated codons are mainly several serines and threonines targeted for phosphorylation by GSK3B.
Product Resources
File Size: 139.35 KBLanguage: English
Resources
Download Files (1)
Data analysis file for qBiomarker™ Somatic Mutation PCR Array Human DNA QC Pathway- FFPE Samples
Catalog number- 337021
Pathway number- SMH-999
Catalog number- 337021
Pathway number- SMH-999
Kit Handbooks (1)
For real-time PCR-based, pathway- or disease-focused somatic mutation profiling
Protocols (8)
User Manuals (2)
For screening disease-focused mutation panels by PCR
For gene expression and genomic analysis
White Papers (1)
Safety Data Sheets (1)
Download Safety Data Sheets for QIAGEN product components.
Certificates of Analysis (1)
Introducing the qBiomarker™ Somatic Mutation PCR Array Human APC/CTNNB1 (beta-catenin) Pathway, a cutting-edge addition to our qBiomarker Somatic Mutation PCR Arrays lineup, specifically designed for Mutation/Variant Detection applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the qBiomarker™ Somatic Mutation PCR Array Human APC/CTNNB1 (beta-catenin) Pathway facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting Mutation/Variant Detection, or any other sophisticated analyses, this product from our qBiomarker Somatic Mutation PCR Arrays collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with qBiomarker™ Somatic Mutation PCR Array Human APC/CTNNB1 (beta-catenin) Pathway and elevate your work to new heights.