Target List
For DNA sequencing, covers all exons in all known transcripts of targeted genes based on the Human GRCh37 / hg19 genome build. For RNA sequencing, covers specific sides of specific exons of the targeted genes based on the Human GRCh38 genome build.
Bladder Cancer
ARID1A, BRCA1, CDKN1A (p21CIP1, WAF1), CDKN2A (P16INK4A), CHD4, CTNNB1, ERBB2 (HER-2, NEU), FBXW7, FGFR3, HRAS, KDM6A, KRAS, MSH6, PBRM1, PIK3CA (p110-alpha), PMS2, PTPRD, PTPRT, SMARCA4, STAG2, TERT, TP53 (p53), TP63, TSC1, TSC2
Brain Cancer
ATRX, BRAF, CDKN2A (P16INK4A), CHEK2 (RAD53), CIC, CTNNB1, CUX1, EGFR (ERBB1), FGFR1, H3-3A, IDH1, IDH2, MAGI2, NF1, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PTCH1, PTEN, PTPRD, PTPRT, SMARCA4, TERT, TP53 (p53), TP63, TSC2
Glioblastomas
CDK4, KDR (VEGFR3), PDGFRA
Gliomas
BRAF, FGFR1, FGFR3, NTRK2, PDGFRA, RAF1, ROS1
Neuroblastomas
EWSR1, FLI1
Breast Cancer:
Basal (Triple-Negative) Carcinomas
ATR, BLM, BRCA1, BRCA2, CASP8 (FLICE), CDH1 (E-Cadherin), CDKN2A (P16INK4A), EGFR (ERBB1), ERBB2 (HER-2, NEU), ERBB3, FGFR1, KMT2C, KRAS, MED12, MSH6, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PMS2, PTEN, RAD51C, RB1, SMARCA4, TP53 (p53), XRCC2
Ductal Carcinomas
AKT1, APC, ATM, ATR, BRCA1, BRCA2, CDH1 (E-Cadherin), CDKN2A (P16INK4A), EGFR (ERBB1), ERBB2 (HER-2, NEU), FANCC, FGFR2, GATA3, GEN1, HOXB13, KMT2C, KRAS, MED12, MLH1, MSH2, NF1, PALB2, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PTEN, RAD51D, SMAD4 (MADH4), STK11 (LKB1), TP53 (p53)
ER-Positive & PR-Positive Carcinomas
ACVR1B, AKT1, APC, CBFB, CDH1 (E-Cadherin), ERBB3, KRAS, MLH1, PIK3CA (p110-alpha), PTEN, TP53 (p53)
HER-Positive Carcinomas
APC, AR, BMPR1A (ALK3), CASP8 (FLICE), CDH1 (E-Cadherin), CDK4, KMT2C, MLH1, MSH6, NCOR1, NF1, PALB2, PIK3CA (p110-alpha), RAD50, SMAD4 (MADH4), STK11 (LKB1), TP53 (p53)
Lobular Carcinomas
AKT1, ATR, CDH1 (E-Cadherin), ERBB2 (HER-2, NEU), MSH2, NF1, PALB2, PIK3CA (p110-alpha), RB1, TP53 (p53), VHL
Luminal Carcinomas
APC, CDH1 (E-Cadherin), CDKN2A (P16INK4A), GATA3, KRAS, MAP2K4 (MKK4, JNKK1), NBN, PIK3CA (p110-alpha), PTEN, TP53 (p53)
Other Carcinomas
APC, AR, ATR, AXIN2, BARD1, BRIP1, CASP8 (FLICE), CDK6, CHEK2 (RAD53), CTNNB1, ERCC4, ABRAXAS1, FANCC, GEN1, HOXB13, KRAS, MED12, MEN1, MSH6, MUTYH, NBN, NF1, PALB2, PIK3CA (p110-alpha), PMS1, PMS2, PTEN, RAD50, RAD51, RAD51C, SMAD4 (MADH4), SMARCA4, STK11 (LKB1)
Other Carcinoma-Related Genes
BAP1, EP300, ESR1 (ERα), MAP3K1 (MEKK1), MDM2, MYC, PBRM1
Other Breast Cancer Genes
CCND1, CUX1, EPCAM, ERG, FOXP1, MAGI2, NRG1 (HGL), NTRK3, PTPRD, PTPRT, RUNX1T1
Cervical Cancer
ARID1A, BCOR, BRCA1, CASP8 (FLICE), CDKN2A (P16INK4A), CHD4, CTNNB1, CUX1, ERBB2 (HER-2, NEU), FBXW7, FGFR2, GNAS, HRAS, KMT2C, KRAS, MAGI2, NTRK3, PIK3CA (p110-alpha), PTPRD, PTPRT, RUNX1T1, SMARCA4, TP53 (p53), TSC1, TSC2
Colorectal Cancer
Adenocarcinomas
ACVR1B, AKT1, APC, ATM, AXIN2, BLM, BMPR1A (ALK3), BRAF, BRCA1, BRCA2, CASP8 (FLICE), CDH1 (E-Cadherin), CDK4, CDKN2A (P16INK4A), CHEK2 (RAD53), CTNNA1, CTNNB1, EGFR (ERBB1), EP300, EPCAM, ERBB2 (HER-2, NEU), FBXW7, FGFR3, FLCN, GREM1, KIT (CD117), KRAS, MAP2K4 (MKK4, JNKK1), MET, MLH1, MSH2, MSH3, MSH6, MUTYH, NRAS, PALB2, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PMS1, PMS2, POLD1, POLE, PTEN, RET, SMAD2 (MADH2), SMAD4 (MADH4), SRC, STK11 (LKB1), TCF7L2, TGFBR2, TP53 (p53), ERBB2 (HER-2, NEU), FLT1 (VEGFR1), NTRK1, NTRK3
Other Colorectal Cancers
APC, BRAF, BRCA2, CDKN2A (P16INK4A), CTNNB1, FBXW7, KRAS, NRAS, PIK3CA (p110-alpha), SMAD4 (MADH4), STK11 (LKB1), TCF7L2, TP53 (p53)
Other Colorectal Cancer Genes
CTNNA1, GNAS, HRAS, PALB2, PMS2, PTPRD, PTPRT, RNF43, RUNX1T1, SMARCA4, SRC, TSC2
Lynch Syndrome
MSH2
Gastric Cancer
ARID1A, BRAF, CDH1 (E-Cadherin), CTNNB1, CUX1, EPHA5, ERBB2 (HER-2, NEU), FGFR1, FGFR2, GNAS, KIT (CD117), KRAS, MAGI2, MET, MLH1, NRG1 (HGL), NTRK3, PDGFRA, PTPRD, PTPRT, RUNX1T1, SLIT2, SMARCA4, TP53 (p53), TSC2, CSF1R, ERBB2 (HER-2, NEU)
Leukemia
Acute Lymphoblastic Leukemia (ALL)
ASXL2, ATM, BRAF, CALR, CDKN2A (P16INK4A), CREBBP (CBP), CRLF2 (TSLPR), CSF3R (GM-CSFR), CTCF, EGFR (ERBB1), EP300, FBXW7, GATA2, HNRNPK, HRAS, IL7R, KDM6A, KDR (VEGFR3), KMT2C, MAP2K1, MLH1, MSH2, MSH6, NOTCH1, NTRK3, PAX5, PDGFRA, PMS2, PTEN, SMARCB1, ABL1, CSF1R, EWSR1, FGFR1, FLT3, JAK2, KMT2A, MLLT3, MYC, NOTCH1, PDGFRB
Acute Myeloid Leukemia (AML)
ASXL1, ATM, BCOR, BCORL1, BIRC3 (c-IAP2), BRAF, CALR, CARD11, CDKN2A (P16INK4A), CEBPA, CHEK2 (RAD53), CREBBP (CBP), CSF1R, CSF3R (GM-CSFR), CTCF, DAXX, DDX41, DNMT1, EP300, FLT3, GATA1, GATA2, HNRNPK, IDH1, IDH2, IKZF1, IL7R, JAK1, JAK3, KDM6A, KDR (VEGFR3), KIT (CD117), KMT2A, KMT2C, KRAS, MAP2K1, MPL, MSH6, MYC, NBN, ANKRD26, NOTCH1, NPM1, NRAS, NSD1, NTRK3, PDGFRA, PHF6, PTEN, PTPN11, RAD21, RUNX1 (AML1), SMARCB1, SMC1A, SMC3, SRSF2, STAG2, U2AF1, WT1, ABL1, ALK, ERG, FGFR1, JAK2, KMT2A, MLLT3, NTRK3, PDGFRA, PDGFRB
Chronic Lymphocytic Leukemia (CLL)
BIRC3 (c-IAP2), BLM, BRAF, CALR, CHEK2 (RAD53), CSF3R (GM-CSFR), KLHL6, KMT2C, MAP2K1, NBN, NTRK3, TERT, MYC, NOTCH1
Chronic Myeloid Leukemia (CML)
ABL1, CALR, CDKN2A (P16INK4A), CEBPA, CREBBP (CBP), CSF1R, CSF3R (GM-CSFR), FBXW7, GATA2, KDM6A, MSH2, MSH6, RB1, SMC1A, TP53 (p53), ABL1, JAK2, PDGFRB
Chronic Myelomonocytic Leukemia (CMML)
CALR, CEBPA, CSF1R, CSF3R (GM-CSFR), HRAS, KMT2C, SRSF2, KMT2A
Chronic Neutrophilic Leukemia (CNL)
CALR, CSF3R (GM-CSFR)
Other Leukemia
ABL1, ERG, EWSR1, JAK2, KMT2A, MYC, NOTCH1, TP53 (p53)
Liver Cancer
CTNNB1, CUX1, EPHA5, ERG, ESR1 (ERα), FGFR2, FOXP1, HNF1A, IKZF1, INPP4B, MAGI2, NRG1 (HGL), NTRK2, NTRK3, PAK3, PAX5, PTPRD, PTPRT, RUNX1T1, SLIT2, SMARCA4, TCF7L2, TP53 (p53), TP63, TSC2, ERBB2 (HER-2, NEU), FGFR2
Lung Cancer
Non-Small Cell Lung Cancers (NSCLC)
ALK, AMER1, APC, ATM, BRAF, CDKN2A (P16INK4A), CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), FGFR3, HRAS, JAK2, KRAS, MET, NF1, NFE2L2, NRAS, NTRK2, NTRK3, PDGFRA, PIK3CA (p110-alpha), PIK3CG, PTEN, RB1, RET, SMARCA4, STK11 (LKB1), TNFAIP3, TP53 (p53), ALK, EGFR (ERBB1), EML4, FGFR1, FGFR3, FGFR4, KIF5B, MET, NRG1 (HGL), NTRK1, NTRK3, RET, ROS1
Small Cell Lung Cancer
ALK, AMER1, ARID1A, ATM, CDKN2A (P16INK4A), CREBBP (CBP), CTNNB1, DDR2, EGFR (ERBB1), EPHA5, ERBB4, FBXW7, FGFR1, HRAS, KDR (VEGFR3), KIT (CD117), KMT2D, KRAS, LRP1B, MET, MYC, NF1, NOTCH1, NTRK1, NTRK2, NTRK3, PIK3CA (p110-alpha), PIK3CG, PIK3R1 (p85-ALPHA), PTEN, PTPRD, RB1, RBM10, RET, RIT1, ROS1, RUNX1T1, SETD2, SMARCA4, TNFAIP3, TP53 (p53)
Adenocarcinomas
AKT1, ALK, AMER1, APC, ARID1A, ATM, BAP1, BRAF, CDKN2A (P16INK4A), CDKN2B (p15INK4b), CREBBP (CBP), CTNNB1, DDR2, EGFR (ERBB1), EPHA5, ERBB2 (HER-2, NEU), ERBB4, FBXW7, FGFR1, FGFR2, FGFR3, HRAS, JAK2, KDR (VEGFR3), KEAP1, KIT (CD117), KMT2D, KRAS, LRP1B, MAP2K1, MDM2, MET, MGA, MLH1, MYC, NF1, NFE2L2, NOTCH1, NRAS, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA (p110-alpha), PIK3CG, PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PTEN, PTPRD, RB1, RBM10, RET, RIT1, ROS1, RUNX1T1, SETD2, SMAD4 (MADH4), SMARCA4, SOX2, STK11 (LKB1), TNFAIP3, TP53 (p53), TSC1, U2AF1, ALK, BRAF, EML4, ERBB2 (HER-2, NEU), FGFR2, FGFR3, KIF5B, MET, NRG1 (HGL), NTRK1, NTRK2, RET, ROS1, RPS6KB1
Other Adenocarcinomas
BRAF, CDKN2A (P16INK4A), CREBBP (CBP), DDR2, EGFR (ERBB1), ERBB2 (HER-2, NEU), KRAS, NF1, STK11 (LKB1), TP53 (p53), ALK, EML4, KIF5B, NRG1 (HGL), ROS1
Squamous Cell Carcinomas (SCC)
AKT1, ALK, AMER1, APC, ARID1A, ATM, BRAF, CDKN2A (P16INK4A), CDKN2B (p15INK4b), CREBBP (CBP), CTNNB1, DDR2, EGFR (ERBB1), EPHA5, ERBB2 (HER-2, NEU), ERBB4, FBXW7, FGFR1, FGFR2, FGFR3, HRAS, JAK2, KDR (VEGFR3), KEAP1, KIT (CD117), KMT2D, KRAS, LRP1B, MAP2K1, MDM2, MET, MGA, MLH1, MYC, NF1, NFE2L2, NOTCH1, NRAS, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA (p110-alpha), PIK3CG, PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PTEN, PTPRD, RB1, RBM10, RET, RIT1, ROS1, RUNX1T1, SETD2, SMAD4 (MADH4), SMARCA4, STK11 (LKB1), TNFAIP3, TP53 (p53), TSC1, U2AF1, ALK, EML4, ERBB2 (HER-2, NEU), FGFR2, FGFR3, KIF5B, KIT (CD117), NRG1 (HGL), RET
Large Cell Carcinomas
BRAF, CDKN2A (P16INK4A), DDR2, EGFR (ERBB1), EPHA5, FGFR1, FGFR3, HRAS, KEAP1, KRAS, NRAS, NTRK1, NTRK3, PIK3CA (p110-alpha), STK11 (LKB1), TP53 (p53)
Other Carcinomas
ARID1A, CREBBP (CBP), CTNNB1, DDR2, EGFR (ERBB1), HRAS, KIT (CD117), KRAS, NRAS, PIK3CA (p110-alpha), STK11 (LKB1), TP53 (p53), ALK, EGFR (ERBB1), EML4, KIF5B, RET, ROS1
Other Lung Cancer Genes
CTNNB1, KRAS, PIK3CA (p110-alpha), PTPRT, TP53 (p53), TSC2
Inflammatory Myofibroblastic Tumors
ALK, EML4, ROS1
Melanoma
BRAF, CDKN2A (P16INK4A), CTNNB1, CUX1, FGFR2, GNA11, GNAQ, GRIN2A, IKZF1, KIT (CD117), MAGI2, MAP2K1, NF1, NRAS, NTRK3, PDGFRA, PIK3CA (p110-alpha), PTEN, PTPRD, PTPRT, RUNX1T1, SMARCA4, TP53 (p53), TP63, TSC2
Myeloid Neoplasms
Multiple Myeloma
ATM, BCL6, BCR, BIRC3 (c-IAP2), BRAF, CDKN2A (P16INK4A), CEBPA, EGFR (ERBB1), FBXW7, HRAS, KDM6A, MYC, NOTCH1, PTEN, SH2D1A, SMARCB1
Myelodysplastic Syndromes (MDS)
ATRX, CALR, CDKN2A (P16INK4A), CEBPA, CSF1R, CSF3R (GM-CSFR), EP300, GNAS, HRAS, KDM6A, KMT2A, KMT2C, RAD21, RB1, SETBP1, SMC3, SRSF2, STAG2, U2AF1, XPO1, ZRSR2, ABL1, ALK, ERG, FGFR1, JAK2, KMT2A, PDGFRB
Myelofibrosis (MF)
CALR, CHEK2 (RAD53), CSF1R, IDH1, IDH2, SRSF2
Myeloid Malignancies
CBL, DNMT3A, EED, ETV6, EZH2, SUZ12, TET2, TP53 (p53)
Myeloproliferative Neoplasms (MPN)
ABL1, ASXL1, CALR, CSF1R, JAK2, JAK3, KAT6A, KRAS, MPL, NF1, NRAS, RB1, SETBP1, SF3B1, SH2B3, SRSF2, STAG2
Other Myeloid Neoplasms
ABL1, ASXL1, BRAF, CALR, CDKN2A (P16INK4A), CEBPA, DNMT3A, ETV6, EZH2, FBXW7, FLT3, GATA2, HRAS, IDH1, IDH2, JAK2, KIT (CD117), KMT2C, KRAS, MAGI2, MPL, MSH6, MYD88, NPM1, NTRK3, PTEN, RUNX1 (AML1), SF3B1, SRSF2, TET2, TP53 (p53), WT1
Other Myeloid Neoplasm Genes
BRCA1, BRCA2, CUX1, FAS, MYD88, STAT3, TERC
Myeloproliferative Neoplasms
ABL1, FGFR1, FLT3, JAK2, PDGFRA, PDGFRB
NUT Midline Carcinoma
NUTM1
Ovarian Cancer
ARID1A, BRAF, BRCA1, BRCA2, CDKN2A (P16INK4A), CTNNB1, CUX1, DICER1, EPHA5, ERG, FOXL2, FOXP1, KRAS, MAGI2, NRG1 (HGL), NTRK3, PAX5, PDGFRA, PIK3CA (p110-alpha), PTPRD, PTPRT, RUNX1T1, SMARCA4, TP53 (p53), TP63, AXL, BRCA1, BRCA2
Pancreatic Cancer
ANKRD11, AR, CDKN2A (P16INK4A), CTNNB1, CUX1, EPHA5, ERBB4, ERG, ESR1 (ERα), FOXP1, GNAS, IKZF1, KRAS, MAGI2, NRG1 (HGL), NTRK2, NTRK3, PTPRD, PTPRT, RUNX1T1, SLIT2, SMAD4 (MADH4), SMARCA4, TCF7L2, TP53 (p53)
Adenocarcinomas
AKT3, BRAF, ERG, ETV1, ETV4, ETV5, PIK3CA (p110-alpha), RAF1, TMPRSS2
Carcinomas
BRAF, RAF1
Prostate Cancer
AR, CTNNB1, CUX1, EPHA5, ERBB4, ERG, ESR1 (ERα), FGFR2, FOXP1, GRIN2A, IKZF1, INPP4B, MAGI2, NRG1 (HGL), NTRK2, NTRK3, PAX5, PTPRD, PTPRT, RAD51B, RUNX1T1, SMARCA4, SPOP, TCF7L2, TP53 (p53)
Adenocarcinomas
AKT3, AR, AXL, BRAF, ERG, ETV1, ETV4, ETV5, FLT1 (VEGFR1), PIK3CA (p110-alpha), RAF1, TMPRSS2
Carcinomas
ERG, ETV1, TMPRSS2
Other Prostate Cancers
ERG, TMPRSS2, TP53 (p53)
Sarcoma
ALK, APC, BRAF, CDK4, CTNNB1, ETV6, EWSR1, FOXO1, GLI1, HRAS, KIT (CD117), KRAS, MDM2, MYOD1, NAB2, NF1, PAX3, PAX7, PDGFRA, PDGFRB, SDHB, SDHC, SMARCB1, TFE3, TP53 (p53)
Askins Tumors
ERG, EWSR1, FLI1
Biphenotypic Sarcomas with Myogenic & Neural Differentiation
EWSR1, FLI1, PAX3
Clear Cell Sarcomas
EWSR1, FLI1
Congenital (Infantile) Fibrosarcomas
MET, NTRK3
Desmoplastic Small Round Cell Tumors
ERG, EWSR1, FLI1
Ewing's Sarcomas
ERG, ETV1, ETV4, EWSR1, FLI1
Fibrosarcomas
BRAF, EWSR1, NTRK1
Myofibroblastic Sarcomas
ALK, NTRK1, ROS1
Rhabdomyosarcomas
EWSR1, FLI1, PAX3, PAX7
Small Round Cell Tumors
ERG, ETV1, EWSR1, FLI1, PAX3
Undifferentiated; Unclassified or Other Sarcomas
ERG, ETV4, EWSR1, FGFR1, FLI1, PAX3
Thyroid Cancer
BCOR, BRAF, CDKN2A (P16INK4A), CTNNB1, CUX1, DICER1, FGFR1, GNAS, HRAS, KRAS, MEN1, NF2, NRAS, PBRM1, PIK3CA (p110-alpha), PTPRD, RBM10, RET, SMARCA4, TERT, TP53 (p53), TSC1, TSC2, TSHR, VEGFA
Adenoma-Nodule-Goitre
PPARG, RET
Anaplastic Carcinomas
ALK, RET
Papillary Carcinomas
ALK, BRAF, EML4, NTRK1, NTRK3, PPARG, RET
Oncogenes
ABL1, AKT1, AKT2, ALK, AR, BCL2, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BRAF, CARD11, CASP8 (FLICE), CBL, CDK4, CRKL, CRLF2 (TSLPR), CSF1R, CTNNB1, DNMT3A, EGFR (ERBB1), ERBB2 (HER-2, NEU), ESR1 (ERα), ETS1, EZH2, FGFR2, FGFR3, FLT3, FOXL2, GATA2, GNA11, GNAQ, GNAS, H3-3A, HGF, H3C2, HRAS, IDH1, IDH2, IKBKE, JAK1, JAK2, JAK3, JUN, KIT (CD117), KRAS, MAP2K1, MCL1, MDM2, MED12, MET, MPL, MYB, MYC, MYCN, MYD88, NFE2L2, NFKBIA (IκBα, MAD3), NRAS, PDGFRA, PIK3CA (p110-alpha), PPP2R1A, PTPN11, RAF1, RARA, REL, RET, ROS1, RUNX1 (AML1), SETBP1, SF3B1, SMO, SPOP, SRC, SRSF2, STAT3, TSHR, U2AF1
Tumor Suppressor Genes
ACVR1B, AMER1, APC, ARID1A, ARID1B, ARID2, ARID5B, ASXL1, ASXL2, ATM, ATRX, AXIN1, B2M, BAP1, BARD1, BCOR, BRCA1, BRCA2, CDC73, CDH1 (E-Cadherin), CDKN2A (P16INK4A), CDKN2B (p15INK4b), CEBPA, CIC, CREBBP (CBP), CYLD, DAXX, EP300, FAT1, FBXW7, FLCN, FOXP1, FUBP1, GATA1, GATA3, HNF1A, KDM5C, KDM6A, KMT2C, KMT2D, MAP3K1 (MEKK1), MEN1, MLH1, MSH2, MSH6, NF1, NF2, NOTCH1, NOTCH2, NPM1, PAX5, PBRM1, PHF6, PIK3R1 (p85-ALPHA), PRDM1, PTCH1, PTEN, RB1, RNF43, SETD2, SMAD2 (MADH2), SMAD4 (MADH4), SMARCA4, SMARCB1, SOCS1, SOX9, STAG2, STK11 (LKB1), TET2, TNFAIP3, TP53 (p53), TSC1, TSC2, VHL, WT1, ZFHX3
Receptor Tyrosine Kinases
ALK, AXL, CSF1R, DDR2, EGFR (ERBB1), EPHA3, EPHA5, EPHA7, EPHB1, ERBB2 (HER-2, NEU), ERBB3, ERBB4, FGFR1, FGFR2, FGFR3, FGFR4, FLT1 (VEGFR1), FLT3, FLT4 (VEGFR2), IGF1R, INSR, KDR (VEGFR3), KIT (CD117), MET, MST1R (RON), NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, RET, ROS1, TGFBR2
Non-Receptor Tyrosine Kinases
ABL1, ABL2 (ARG), BTK, FYN, JAK1, JAK2, JAK3, LYN, SRC, SYK, YES1
Epithelial-to-Mesenchymal Transition (EMT)
BRCA2, CDKN2B (p15INK4b), CTNNB1, ERBB2 (HER-2, NEU), HGF, JAK2, KIT (CD117), MCL1, NF1, NOTCH1, SMAD4 (MADH4), SRC, VHL
Tumor Metastasis
AXL, ERBB3, HGF, IRF4, MAX, MET, NF1
Cancer Therapeutic Targets
AKT1, ATM, AXL, BCL2, BCL6, BTK, CHEK1, CTNNB1, CXCR4, EPCAM, GSK3B, HSP90AA1, JAK2, MCL1, MTOR, NOTCH1, PARP1 (ADPRT1), PTCH1, SMO, SRC, STAT3, SYK, TGFBR1 (ALK5)
Angiogenesis
AKT1, AKT2, AKT3, BTG1, CASP8 (FLICE), CTNNB1, EGFL7, ERBB2 (HER-2, NEU), FGF1, FGF2 (BFGF), FGF6, FGFR2, FLT1 (VEGFR1), FLT4 (VEGFR2), GATA2, GREM1, HOXB13, JUN, KDR (VEGFR3), NF1, NOTCH1, PDGFRA, PIK3CA (p110-alpha), PTEN, RUNX1 (AML1), SLIT2, TGFBR2, TNFAIP3, VEGFA, VHL
Apoptosis
ABL1, ABL2 (ARG), ACVR1 (ALK2), AKT1, AKT2, AKT3, APC, ARAF, ATM, AXIN1, BARD1, BBC3 (PUMA), BCL2, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L11, BCL2L2, BCL6, BIRC3 (c-IAP2), BRAF, BRCA1, BTG1, CASP8 (FLICE), CBL, CDH1 (E-Cadherin), CDKN1A (p21CIP1, WAF1), CDKN1B (P27KIP1), CDKN2A (P16INK4A), CHEK2 (RAD53), CTNNA1, CTNNB1, CXCR4, CYLD, DAXX, EGFR (ERBB1), EP300, ERBB2 (HER-2, NEU), ERBB3, ETV1, FAS, FLT3, FOXL2, GATA1, HGF, HRAS, ID3, IGF1, IGF1R, IL10, IRS1, JUN, KRAS, MAP2K1, MAP2K4 (MKK4, JNKK1), MAPK1 (ERK2), MAPK3 (ERK1), MCL1, MDM4, MLH1, MSH2, MYC, MYCN, NF1, NFKBIA (IκBα, MAD3), NPM1, NUP93, PDK1, PIK3R2 (p85-BETA), PIM1, PRKCI, PRKDC, PTEN, RAD21, RAD50, RAD51, RAF1, RASA1, RB1, REL, RHOA, RYBP, SNCAIP, SOX9, STAT3, STK11 (LKB1), TERT, TNFAIP3, TOP2A, TP53 (p53), TRAF2, TRAF7, VEGFA, VHL, WT1, XIAP
Autophagy
AKT1, BCL2, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), CASP8 (FLICE), CDKN1B (P27KIP1), CDKN2A (P16INK4A), CXCR4, ESR1 (ERα), FAS, HSP90AA1, IGF1, LAMP1, MTOR, PIK3C3 (VPS34), PIK3CG, PTEN, RB1, RPS6KB1, TP53 (p53)
Cell Adhesion Molecules
ABL1, ABL2 (ARG), APC, CDH1 (E-Cadherin), CSF3R (GM-CSFR), CTNNA1, CTNNB1, DDR2, EGFL7, EGFR (ERBB1), EPCAM, ERBB2 (HER-2, NEU), FAT1, FGF4, GATA1, JAK2, KDR (VEGFR3), KEL, NEGR1, NF1, NF2, NOTCH1, PDGFRA, PTEN, PTPN11, PTPRS, RAC1, RET, RHOA, SRC, SYK, TSC1
Cell Cycle
ABL1, ABL2 (ARG), ACVR1 (ALK2), AKT1, AKT2, AKT3, APC, ATM, ATR, AURKA, AURKB, AXIN1, BCL2, BCR, BLM, BRCA1, BRCA2, BRD4, CCND1, CCND2, CCND3, CCNE1, CDC73, CDK12, CDK4, CDK6, CDK8, CDKN1A (p21CIP1, WAF1), CDKN1B (P27KIP1), CDKN2A (P16INK4A), CDKN2B (p15INK4b), CDKN2C (p18-INK4C), CENPA, CHEK1, CHEK2 (RAD53), CREBBP (CBP), CUL3, CUX1, CYLD, DIS3, EGFR (ERBB1), EP300, FBXW7, FGFR2, HGF, HRAS, ID3, IGF1, IGF2, INHBA, JAK2, JUN, KLF4, KRAS, MAPK1 (ERK2), MAPK3 (ERK1), MDC1, MDM2, MDM4, MEN1, MLH1, MYC, NBN, NF2, NOTCH2, NPM1, NRAS, PDK1, PIM1, PLK2, PPM1D, PTEN, PTPRD, RAD21, RAD50, RAD51, RB1, RHEB, RHOA, SMARCA4, SMARCB1, SMC1A, SMC3, SOX2, SOX9, STAG1, STAG2, STK11 (LKB1), TCF3, TERT, TNFAIP3, TP53 (p53), TSC1, VEGFA, XPO1, ZFHX3
Cell Growth & Proliferation
ACVR1 (ALK2), AKT1, AR, BCL2, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BLM, BRAF, BTG1, CCND1, CDKN1B (P27KIP1), CDKN2A (P16INK4A), CSF1R, CTNNB1, CXCR4, EGFR (ERBB1), ERBB2 (HER-2, NEU), EWSR1, FGFR4, FLT4 (VEGFR2), HGF, HRAS, IGF1, IL10, INSR, KRAS, MAPK1 (ERK2), MAPK3 (ERK1), MDM2, MET, MPL, MYC, NF2, NFKBIA (IκBα, MAD3), NPM1, NRAS, PAK7, PAX5, PDGFRA, PIK3R2 (p85-BETA), PIM1, PTEN, RAF1, RASA1, SMAD3 (MADH3), SOCS1, SRC, SYK, TGFBR2, TMEM127, TP53 (p53), TSHR, VEGFA
Cell Migration
ACVR1 (ALK2), AR, AXL, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), CDKN1B (P27KIP1), CTNNB1, EGFR (ERBB1), FGF7, IGF1, IL10, IRS1, MAP2K1, MYC, NFKBIA (IκBα, MAD3), PDGFRA, PTEN, SMO, STAT3, TGFBR2, VEGFA
Cellular Senescence
ABL1, AKT1, ATM, CALR, CCND1, CCNE1, CDK4, CDK6, CDKN1A (p21CIP1, WAF1), CDKN1B (P27KIP1), CDKN2A (P16INK4A), CDKN2B (p15INK4b), CDKN2C (p18-INK4C), CHEK1, CHEK2 (RAD53), E2F3, ETS1, GSK3B, HRAS, IGF1, IGF1R, MAP2K1, MDM2, MYC, NBN, PIK3CA (p110-alpha), PTEN, RB1, TBX3, TERT, TP53 (p53)
Cytoskeleton Regulators
EML4, KIF5B, PAK7, SPTA1
DNA Damage & Repair
ABL1, ABL2 (ARG), APC, ATM, ATR, ATRX, AXIN2, BARD1, BLM, BRCA1, BRCA2, BRIP1, C11orf30, CCND1, CDKN1A (p21CIP1, WAF1), CHEK1, CHEK2 (RAD53), EP300, EPCAM, ERCC1, ERCC2 (XPD), ERCC3 (XPB), ERCC4, ERCC5, ABRAXAS1, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, GEN1, MAPK1 (ERK2), MDC1, MDM2, MEN1, MLH1, MRE11, MSH2, MSH3, MSH6, MTOR, MUTYH, NBN, NPM1, PALB2, PARP1 (ADPRT1), PIK3C2B, PMS1, PMS2, POLD1, POLE, PRKDC, RAD21, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54L, RECQL4, SETD2, SMC1A, SMC3, STK11 (LKB1), TERT, TP53 (p53), XIAP, XRCC2
Epigenetics
ARID1A, ARID1B, ARID2, ARID5B, ASXL1, ASXL2, ATRX, AURKA, AURKB, BAP1, BCOR, BCORL1, BRD4, CENPA, CHD2, CHD4, CTCF, DICER1, DNMT1, DNMT3A, DNMT3B, DOT1L, EED, EZH2, FOXA1, H3-3A, H3F3B, H3F3C, HIST1H1C, HIST1H2BD, HIST1H3A, H3C2, HIST1H3C, H3C4, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST2H3A, HIST2H3C, HIST2H3D, HIST3H3, IKZF1, KAT6A, KDM5A, KDM5C, KDM6A, KMT2A, KMT2B, KMT2C, KMT2D, MLLT3, NCOR1, NSD1, PBRM1, PHF6, PRDM1, RARA, RUNX1T1, RYBP, SETBP1, SETD2, SMARCA4, SMARCB1, SMARCD1, SPOP, SUZ12, TCF3, TET1, TET2, TOP1
Growth Factors & Receptors
EGFR (ERBB1), ERBB2 (HER-2, NEU), ERBB3, ERBB4, FGF10, FGF14, FGF2 (BFGF), FGF23, FGF5, FGF8, FLT1 (VEGFR1), FLT4 (VEGFR2), IGF1, IGF1R, IGF2, KDR (VEGFR3), KIT (CD117), MET, PDGFRA, PDGFRB, VEGFA
Hormone Receptors
AR, ESR1 (ERα), PGR, PPARG, RARA
Immune Checkpoint Molecules
B2M, CD274 (PD-L1), CD274 (PD-L1), CD276, CD74, CTLA4, HLA-A, HLA-B, HLA-C, ICOSLG, PDCD1 (PD1), PDCD1 (PD1), PDCD1LG2, TNFRSF14, VTCN1
Immune Response
ALK, B2M, BTK, CARD11, CD274 (PD-L1), CD274 (PD-L1), CD276, CD79A, CD79B, CREBBP (CBP), CRLF2 (TSLPR), CXCR4, CYLD, EP300, FAM46C, IL7R, IRF4, JAK1, JAK2, JAK3, MAP2K1, MAP2K2 (MEK2), MAP3K1 (MEKK1), MCL1, MYD88, NFKBIA (IκBα, MAD3), PAX5, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PTEN, PTPN11, REL, TNFAIP3, TNFRSF14, TP53 (p53)
Inflammatory Response
BCR, CEBPA, CSF1R, CXCR4, JAK2, MYD88, REL, TNFAIP3
Metabolism
AKT1, AKT2, AKT3, ALOX12B, ASXL2, DNAJB1, FH, FLCN, HSD3B1, IDH1, IDH2, IGF1, MTOR, PDK1, RICTOR, RPTOR, SDHA, SDHAF2, SDHB, SDHC, SDHD, STK11 (LKB1), TSC2
mRNA Splicing
DHX15, QKI, RBM10, SF3B1, SHQ1, SMC1A, SRSF2, U2AF1, ZRSR2
Proteases
KEL, PRSS8, TMPRSS2
Signal Transduction
Androgen Receptor Signaling
AR, CCND1, CTNNB1, DAXX, EGFR (ERBB1), FOXO1, IGF1, PTEN, RB1, TMPRSS2, VEGFA
BCR-ABL Pathway
ABL1, BCR, JAK2, STAT3, STAT5A, STAT5B
CREB Signaling & Targets
BCL2, BRCA1, CCND1, CDKN2B (p15INK4b), FGF6, INHBA, NF1, PMAIP1 (NOXA), PRKAR1A, RB1, STAT3
Estrogen Receptor Signaling & Targets
BRCA1, CCND1, ERBB2 (HER-2, NEU), ESR1 (ERα), FOXA1, HSP90AA1, IGF1, MYC, NCOA3, NCOR1, PGR, PTCH1, RARA
Fibroblast Growth Factor Signaling
AKT1, FGF4, FGF6, FGFR1, FGFR2, FGFR3, FGFR4, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PTEN, PTPN11, SRC
G-Protein Coupled Receptor Signaling
AKT1, GNA11, GNAQ, GNAS, GRM3, SMO, TSHR
G-Protein Signaling
ADGRA2, ARFRP1, CDKN1A (p21CIP1, WAF1), CDKN2A (P16INK4A), GPS2, HRAS, KRAS, NRAS, PAK7, RAB35, RAC1, RAF1, RANBP2, RASA1, RB1, RHOA, SRC, TP53 (p53)
Growth Factor Signaling & Targets
FRS2, HRAS, IGF1, JUN, MAPK1 (ERK2), MAPK3 (ERK1), PDGFRA, STAT3, STAT5A
Hedgehog Signaling & Targets
BCL2, CCND1, CSNK1A1, ERBB4, FGF9, FGFR3, GLI1, GSK3B, MAPK1 (ERK2), PTCH1, SMO, SUFU, TP53 (p53), VEGFA
Hippo Signaling
LATS1, LATS2, NF2, YAP1
Hypoxia Signaling & Targets
ATR, BLM, BTG1, CREBBP (CBP), EP300, MAP3K1 (MEKK1), MET, NF1, PDK1, PIM1, SMAD4 (MADH4), TFRC, VEGFA, VHL
IGF Signaling
HRAS, IGF1, IGF1R, IGF2, IRS1, JUN, MAP2K1, MAPK3 (ERK1), PTPN11, RAF1, RASA1
Insulin Signaling & Targets
AKT1, AKT2, AKT3, FOXO1, INSR, IRF2, IRS1, JUN, MYD88, PDPK1, PIK3CA (p110-alpha), PIK3CB, PIK3CD, PIK3CG, TP53 (p53)
JAK / STAT Signaling & Targets
AKT1, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), CCND1, CDKN1A (p21CIP1, WAF1), CREBBP (CBP), CSF1R, EGFR (ERBB1), FAS, GATA3, IFNGR1, IL10, INSR, JAK1, JAK2, JAK3, MCL1, MPL, MYC, PDGFRA, SOCS1, SRC, STAT3, STAT4, STAT5A, STAT5B
MAP Kinase Signaling & Targets
ARAF, BRAF, CCND1, CCND2, CCND3, CCNE1, CDK4, CDK6, CDKN1A (p21CIP1, WAF1), CDKN1B (P27KIP1), CDKN2A (P16INK4A), CDKN2B (p15INK4b), CDKN2C (p18-INK4C), CEBPA, EGFR (ERBB1), HGF, HRAS, JUN, KRAS, MAP2K1, MAP2K2 (MEK2), MAP2K4 (MKK4, JNKK1), MAP3K1 (MEKK1), MAP3K13, MAP3K14, MAP3K4 (MEKK4), MAPK1 (ERK2), MAPK3 (ERK1), MAX, MST1, MYC, NRAS, PAK1, PDGFRA, PPM1D, RAC1, RAF1, RB1, RHOA, RIT1, SOX2, SRC, STAT3, STK40, TP53 (p53), TRAF7
MET / HGF Signaling
HGF, MET
mTOR Signaling
AKT1, AKT2, AKT3, EIF4E, GSK3B, HRAS, IGF1, INSR, IRS1, MAPK1 (ERK2), MAPK3 (ERK1), MTOR, PDK1, PDPK1, PIK3C3 (VPS34), PIK3CA (p110-alpha), PIK3CB, PIK3CD, PIK3CG, PTEN, RHEB, RHOA, RICTOR, RPS6KA4, RPS6KB1, RPS6KB2, RPTOR, STK11 (LKB1), TMEM127, TP53 (p53), TSC1, TSC2, VEGFA
NFκB Signaling & Targets
AKT1, BCL10, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BIRC3 (c-IAP2), CARD11, CASP8 (FLICE), EGFR (ERBB1), GREM1, IKBKE, IL10, JAK2, JUN, MALT1, MAP3K1 (MEKK1), MYD88, NFKBIA (IκBα, MAD3), RAF1, REL, RHOA, TNFAIP3, TRAF2
Notch Signaling & Targets
AXIN1, CBL, CCND1, CCNE1, CDKN1A (p21CIP1, WAF1), CREBBP (CBP), CTNNB1, EP300, ERBB2 (HER-2, NEU), FBXW7, GATA2, GLI1, NOTCH1, NOTCH2, NOTCH3, NOTCH4, PAX5, PPARG, RUNX1 (AML1), SH2D1A, SUFU
p53 Signaling & Targets
ATM, ATR, BBC3 (PUMA), BRCA1, CDKN1A (p21CIP1, WAF1), CDKN2A (P16INK4A), CHEK1, CHEK2 (RAD53), DNMT1, E2F3, EGFR (ERBB1), ESR1 (ERα), FAS, MDM2, MDM4, MSH2, MYC, PPM1D, PTEN, RB1, TP63
PI3K-AKT Signaling
AKT1, AKT2, AKT3, ALK, APC, AR, BCL2, BTK, CBL, CCND1, CCND2, CDH1 (E-Cadherin), CDKN2A (P16INK4A), CTNNB1, CXCR4, EGFR (ERBB1), ERBB2 (HER-2, NEU), FLT3, FOXO1, GSK3B, HSP90AA1, IGF1, IGF1R, INPP4A, IRS1, JAK2, KDR (VEGFR3), KIT (CD117), MAPK1 (ERK2), MTOR, MYD88, NF1, NFKBIA (IκBα, MAD3), PAK1, PDGFRA, PDK1, PDPK1, PIK3C2G, PIK3C3 (VPS34), PIK3CA (p110-alpha), PIK3CB, PIK3CD, PIK3CG, PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PIK3R3, PREX2, PTEN, SYK, TP53 (p53), VEGFA
PTEN Signaling & Targets
AKT1, CDKN1B (P27KIP1), EGFR (ERBB1), IGF1, MAPK1 (ERK2), MAPK3 (ERK1), PDK1, PDPK1, PTEN, TP53 (p53), VEGFA
TGFβ / BMP Signaling & Targets
ACVR1 (ALK2), ACVR1B, BMPR1A (ALK3), CDKN1A (p21CIP1, WAF1), CDKN1B (P27KIP1), CDKN2B (p15INK4b), CREBBP (CBP), EP300, GREM1, ID3, IGF1, INHA, INHBA, JUN, MYC, RUNX1 (AML1), SMAD2 (MADH2), SMAD3 (MADH3), SMAD4 (MADH4), TGFBR1 (ALK5), TGFBR2
WNT Signaling & Target
AMER1, APC, AXIN1, AXIN2, CCND1, CCND2, CDKN2A (P16INK4A), CREBBP (CBP), CTNNB1, CYLD, EPCAM, FGF9, GSK3B, HNF1A, JUN, LATS1, LATS2, MED12, MYC, PPP2R1A, PPP2R2A, PPP6C, RB1, RNF43, SMAD4 (MADH4), SOX2, TCF7L2, TP53 (p53), TSC2, WISP3
Other Signal Transduction Genes
AXL, CBFB, DDR2, EPHA3, EPHA5, EPHA7, EPHB1, ERBB3, ERRFI1, EWSR1, FGF19, FGF3, FLT1 (VEGFR1), FLT4 (VEGFR2), GABRA6, GNA13, GRIN2A, INPP4B, IRS2, LMO1, NTRK1, NTRK2, NTRK3, PDGFRB, PLCG2, PRKCI, RET, ROS1, SOX17, SPEN
Telomeres & Telomerase
ABL1, AKT1, ATM, BCL2, BLM, CHEK1, CHEK2 (RAD53), ERCC1, ERCC4, HSP90AA1, IGF1, KRAS, MEN1, MSH2, MSH3, MYC, NBN, PARP1 (ADPRT1), PAX8, PPARG, PPP2R1A, PRKDC, RAD50, RB1, RECQL4, SLX4, SMAD3 (MADH3), SMARCD1, TERT, TP53 (p53)
Transcription Factors
ABL1, AKT1, AR, BRCA1, BRCA2, C11orf30, CBL, CDKN2A (P16INK4A), CEBPA, CHD4, CIC, CREBBP (CBP), CTNNB1, CUX1, DAXX, EGFR (ERBB1), EIF4E, EP300, ERG, ESR1 (ERα), ETS1, ETV1, ETV4, ETV5, ETV6, EWSR1, FBXW7, FLI1, FOXA1, FOXL2, FOXO1, FOXP1, FUBP1, GATA1, GATA2, GATA3, GATA4, GATA6, GLI1, HNF1A, HOXB13, ID3, IRF4, JUN, KEAP1, KLF4, LMO1, LZTR1, MAX, MDM2, MEF2B, MEN1, MITF, MLLT3, MYB, MYC, MYCL, MYCN, MYOD1, NF1, NFE2L2, NKX2-1, NKX3-1, NOTCH1, PAX5, PGR, PHOX2B, PNRC1, PPARG, RARA, RB1, REL, RUNX1 (AML1), SMAD2 (MADH2), SMAD3 (MADH3), SMAD4 (MADH4), SOX10, SOX17, SOX2, SOX9, STAT3, STAT5A, SUFU, TAF1, TBX3, TCEB1, TCF3, TCF7L2, TOP1, TP53 (p53), TSC1, VHL, WT1, ZBTB2, ZBTB7A, ZFHX3, ZNF217, ZNF703
Translation
EIF1AX, EIF4A2
Ubiquitination
ASXL2, BAP1, BCOR, CUL3, DAXX, DCUN1D1, GID4, MDM2, PRKN, COP1, RNF43, SNCAIP, TAF1, TCEB1, TRAF7
Unfolded Protein Response
CALR, HSP90AA1, NFE2L2, NPM1
Microsatellite Instability (MSI) Loci
BAT25, BAT26, BAT34C4, BAT40, D10S196, D13S175, D17S250, D17S588, D17S787, D18S35, D18S55, D18S61, D18S64, D18S69, D20S100, D2S123, D3S1029, D5S107, D5S346, D7S519, D8S87, HSP110-T17, MONO-27, NR21, NR22, NR24
Bone Cancer
Askins Tumors
ERG, EWSR1, FLI1
Ewing's Sarcomas
ERG, ETV1, ETV4, EWSR1, FLI1
Giant Cell Tumors
EWSR1, FLI1
Breast Cancer
Adenocarcinomas
ERBB2 (HER-2, NEU), NOTCH1, NOTCH2, RPS6KB1
Carcinomas
ESR1 (ERα), FGFR1, NOTCH1, NTRK3, PIK3CA (p110-alpha), RAF1
Invasive Carcinomas
CSF1R, ERBB2 (HER-2, NEU), KIT (CD117), PIK3CA (p110-alpha), RPS6KB1
Other Breast Cancers
AKT3, NOTCH3
Endometrial Cancer
ERBB2 (HER-2, NEU), PIK3CA (p110-alpha)
Kidney Cancer
ALK, NTRK3
Lymphoma
Anaplastic Large Cell Lymphomas
ALK, MYC
Diffuse Large B Cell Lymphomas (DLBCL)
ALK, MYC
Follicular Lymphomas
BCL2, MYC
Hodgkin Lymphomas
ALK, JAK2, MYC
Lymphoblastic Lymphomas
FGFR1, KMT2A, MLLT3, MYC, NOTCH1, PDGFRB
T Cell Lymphomas
ALK, FGFR1, FGFR3, JAK2, PDGFRA
Other Cancers
ETS1
Salivary Gland Cancer
FGFR1, NTRK3
Skin Cancer
Benign Melanocytic Nevus; Spitz
ALK, BRAF, KIF5B, RET, ROS1, TP53 (p53)
Melanomas
BRAF, EWSR1, TP53 (p53)
Soft Tissue Cancer
Desmoplastic Small Round Cell Tumors
ERG, EWSR1
Inflammatory Myofibroblastic Tumors
ALK
Rhabdomyosarcomas
PAX3, PAX7
Sarcoma
ETV4, EWSR1
Small Round Cell Tumors
ETV1, EWSR1, FLI1
Stomach Cancer
ERBB2 (HER-2, NEU), FLT1 (VEGFR1), PDGFRB
Urinary Tract Cancer
FGFR3, PIK3CA (p110-alpha)
Uterine Cancer
ESR1 (ERα), PIK3CA (p110-alpha)