Target List
Covers all exons in all known transcripts of targeted genes based on the Human GRCh38 genome build
Carcinomas
ATMBARD1BRCA1BRCA2BRIP1CDK12CDK4CHEK1CHEK2 (RAD53)EGFR (ERBB1)ERBB2 (HER-2, NEU)ESR1 (ERα)FANCLKIT (CD117)KRASMETMLH1MLH3MSH2MSH3MSH6PALB2PDGFRAPIK3CA (p110-alpha)PMS1PMS2RAD51BRAD51CRAD51DRAD54L
Ductal Carcinomas
ARCCND1CDH1 (E-Cadherin)CYP2D6FANCD2FBXW7FGFR1FGFR2MRE11MYCNBNNTRK3PPM1DPPP2R1ARB1CC1SF3B1SLC22A18STK11 (LKB1)TP53 (p53)
ER-Positive Carcinomas
CDH1 (E-Cadherin)RB1CC1SF3B1
HER-Positive Carcinomas
ARCCND1FANCD2NTRK3PPM1DRB1CC1
Metastatic Breast Cancers
AKT1BRCA1BRCA2ERBB2 (HER-2, NEU)ERBB3ESR1 (ERα)MDM2NF1PALB2PIK3CA (p110-alpha)PTEN
Mismatch Repair (MMR) Genes
MLH1MSH2MSH6PMS2