Target List
Covers all exons in all known transcripts of targeted genes based on the Human GRCh38 genome build
Anaplastic Glial Tumors
CDKN2A (P16INK4A)CDKN2B (p15INK4b)MDM2PTENRB1TP53 (p53)
Astrocytomas
ATRXBRAFCHEK2 (RAD53)FGFR1IDH1IDH2KRASNOTCH1PTPN11RB1TP53 (p53)
Ependymomas
CDKN2A (P16INK4A)CDKN2B (p15INK4b)H3-3ANF2NOTCH1
Glioblastomas
ALKAPCBCORBRAFCDK4CDK6CDKN2A (P16INK4A)CDKN2B (p15INK4b)CREBBP (CBP)EGFR (ERBB1)ERBB2 (HER-2, NEU)FGFR3H3-3AH3C2IDH1IDH2KIT (CD117)MDM2METMLH1MSH2MTORMYCNOTCH1NRASPIK3CA (p110-alpha)PMS2PTENRB1STK11 (LKB1)TERTTP53 (p53)
Gliomas
ACVR1 (ALK2)BRCA2CHEK2 (RAD53)FGFR1H3-3APDGFRAPIK3CA (p110-alpha)PTENTP53 (p53)
High-Grade Gliomas
ATRXBRAFCICEGFR (ERBB1)FUBP1IDH1IDH2
Medulloblastomas
BRCA2CDK4CREBBP (CBP)CTNNB1FGFR1GLI2IDH1IDH2MSH2MYCMYCNNRASPIK3CA (p110-alpha)PTCH2SMARCA4SMARCB1SUFUTP53 (p53)
Meningiomas
CDKN2A (P16INK4A)CDKN2B (p15INK4b)NF2PTEN
Oligodendrogliomas
IDH1IDH2MSH2NOTCH1TERT