Target List
Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build
Carcinomas
ATMBARD1BRCA1BRCA2BRIP1CDH1 (E-Cadherin)CDK12CDK4CHEK1CHEK2 (RAD53)EGFR (ERBB1)ERBB2 (HER-2, NEU)ESR1 (ERα)FANCLFBXW7KIT (CD117)KRASMETMLH1MLH3MSH2MSH3MSH6PALB2PDGFRAPIK3CA (p110-alpha)PMS1PMS2RAD51BRAD51CRAD51DRAD54LSF3B1
Metastatic Breast Cancers
AKT1BRCA1BRCA2ERBB2 (HER-2, NEU)ERBB3ESR1 (ERα)PALB2PIK3CA (p110-alpha)PTEN
Mismatch Repair (MMR) Genes
MLH1MSH2MSH6PMS2