Target List
Apoptosis
Pro-Apoptotic
Abl1Aifm1Akt1Anxa5BadBak1BaxBbc3Bcl10Bcl2l11BidBikBmfBnip3Bnip3lBokBrca1Card10Casp1 (Ice)Casp12Casp14Casp2Casp3Casp4Casp6Casp8 (Flice)Casp8ap2Cd27Cd28Cd40Cd70Cdkn1a (p21Cip1, Waf1)CidebCraddCycsDaxxDdit3 (Gadd153, Chop)DffaDffbDiablo (Smac)FaddFaf1FasFaslFem1bFoxo3Gadd45aHipk2HrkIfnb1IkbkgIl18Il1bIl24Lta (Tnfb)LtbrMaddMap3k5Mapk1 (Erk2)NgfrBex3Nod1Pidd1Pmaip1 (NoxA)PmlPrkcaPrkcdPycard (Tms1, Asc)Ripk1Ripk2Ripk3SpnTnfTnfrsf10b (Dr5)Tnfrsf25 (Dr3)Tnfrsf8Tnfrsf9Tnfsf10 (Trail)Tnfsf12 (Apo3l)Tnfsf8TraddTraf1Traf2Traf3Trp53 (p53)Trp53bp2Trp63 (Tp73l)
Anti-Apoptotic
Akt1Api5Atf5Bag1Bag3BaxBcl10Bcl2Bcl2a1a (Bfl-1, A1)Bcl2a1bBcl2a1cBcl2a1dBcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Bcl2l10Bcl2l2BfarBirc2 (cIAP1, cIAP2)Birc3 (cIAP1, cIAP2)Birc5Birc6Bnip2Bnip3Bnip3lBrafCasp3Cd27Cd40lgCflar (Casper)CideaCsf2 (GMCSF)Dad1Dapk1DffaFasHrkIgf1rIl10Il2Il4Il6Lhx4Mcl1MycMyd88Naip1 (Birc1)Naip2Naip3Naip5Nfkb1Nfkb2NgfNgfrNme5Nol3PolbRasa1Ripk1Ripk2TnfTnfrsf1a (Tnfr1)Tnfrsf1bTnfrsf4 (Ox40)Traf2Trp53 (p53)Trp63 (Tp73l)Trp73Xiap
Necrosis
Autophagy
Regulation of Autophagy
Akt1AppAtg12Atg5BadBak1BaxBcl2Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Becn1BidBnip3Casp3Casp8 (Flice)Cdkn2a (p16INK4a)Cln3CtsbCtsdCtssCxcr4Dapk1Dram1Dram2Eif2ak3Eif4g1Ern1Esr1 (Erα)FaddFasGaaHdac1HgsHsp90aa1Hspa8HttIfngIgf1Ins2Lamp1Mapk14 (p38alpha)Mapk8 (Jnk1)MtorNfkb1Nlrp4cNlrp4eNod2Pik3c3 (Vps34)Pik3cgPik3r4Pink1Prkaa1 (Ampk)PtenRb1Rps6kb1Sirt1SncaSqstm1Tgfb1Tgm2Tmem74TnfTnfsf10 (Trail)Trp53 (p53)Ulk2Uvrag