GeneGlobe ID: SBHS-131Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels

QuantiNova LNA PCR Focus Panel Human Breast Cancer

QuantiNova LNA PCR Focus Panel
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Product Specification

Target List
Breast Cancer Classification Markers
Luminal A-C Breast Cancers​
ESR1 (ERα), FOXA1, GATA3, KRT8, KRT18, SLC39A6, TFF3, XBP1
HER2-Like Breast Cancers​
ERBB2 (HER-2, NEU), GRB7
Basal-Like / Triple Negative Breast Cancers​
BIRC5, EGFR (ERBB1), KRT5, NOTCH1
Breast Cancer Metastasis to Lung​
ID1, MMP2, PTGS2 (COX2)
Signal Transduction
Steroid Receptor-Mediated Signaling​
AR, BRCA1, CCNE1, CTNNB1, ESR1 (ERα), ESR2 (ERβ), IGF1, KRT19, PGR, RB1
Hedgehog Signaling​
BCL2, CCND1, GLI1, SNAI2
Glucocorticoid Signaling​
IGFBP3, NME1 (NM23), NR3C1 (GRL)
Classical WNT Signaling​
APC, CCND1, CTNNB1, SFRP1
AKT & PI3 Kinase Signaling​
AKT1, ERBB2 (HER-2, NEU), IGF1, IGF1R, PTEN
Notch Signaling​
BIRC5, NOTCH1
MAP Kinase Signaling​
MAPK1 (ERK2), MAPK3 (ERK1), MAPK8 (JNK1), TP73
Epithelial-to-Mesenchymal Transition (EMT)
CTNNB1, NOTCH1, SRC, TGFB1, TWIST1
Angiogenesis
CDH13, CTNNB1, EGF, ERBB2 (HER-2, NEU), ID1, IL6, JUN, NOTCH1, PLAU (UPA), PTEN, SERPINE1 (PAI-1), SLIT2, THBS1 (TSP-1), VEGFA
Cell Adhesion Molecules
ADAM23, APC, BCL2, CDH1 (E-Cadherin), CDH13, CDKN2A (P16INK4A), CSF1 (MCSF), CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), PTEN, TGFB1, THBS1 (TSP-1)
Proteases
ADAM23, CST6, CTSD, MMP2, MMP9, PLAU (UPA), PYCARD (TMS1, ASC)
Apoptosis
AKT1, APC, BAD, BCL2, CDH1 (E-Cadherin), CDKN1A (p21CIP1, WAF1), CDKN2A (P16INK4A), GSTP1, IGF1, IL6, JUN, MUC1 (mucin), NME1 (NM23), RARB, SFN (14-3-3σ, YWHAS), SFRP1, TP53 (p53), TP73, TWIST1
Cell Cycle
APC, BCL2, CCNA1, CCND1, CCND2, CCNE1, CDK2, CDKN1A (p21CIP1, WAF1), CDKN1C (p57Kip2), CDKN2A (P16INK4A), JUN, MKI67, MYC, PTEN, RASSF1, RB1, SFN (14-3-3σ, YWHAS), TP53 (p53)
DNA Damage & Repair
APC, ATM, BRCA1, BRCA2, CCND1, CDKN1A (p21CIP1, WAF1), MAPK1 (ERK2), MGMT (AGT), MLH1, SFN (14-3-3σ, YWHAS), TP53 (p53), TP73
Xenobiotic Transport
ABCB1 (MDR1, PGY1), ABCG2 (BCRP)
Transcription Factors
AR, CTNNB1, ESR1 (ERα), ESR2 (ERβ), FOXA1, GATA3, HIC1, JUN, MYC, NOTCH1, NR3C1 (GRL), PGR, PRDM2 (RIZ1), RARB, RB1, TP53 (p53), TP73, XBP1
Gene Resource List
Array Layout for PCR Plates
File Size: 153.55 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.7 KBLanguage: English

Resources

Quick-Start Protocols (1)
Safety Data Sheets (1)
Kit Handbooks (1)
Certificates of Analysis (1)
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