Target List
Immune & Inflammatory Responses
Immunostimulatory Factors
Ifng, Il2, Il12a, Il12b, Il15, Tnf
Immunosuppressive Factors
Cd274 (Pdl1), Cd274 (Pdl1), Csf2 (GMCSF), Ctla4, Cxcl12, Cxcl5 (ENA-78, LIX), Ido1 (Ido), Ido1 (Ido), Il10, Il13, Il4, Il5, Mif, Nos2 (iNos), Pdcd1 (PD-1), Pdcd1 (PD-1), Ptgs2 (Cox2), Tgfb1, Vegfa
Pro-inflammatory Genes
Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl20 (Mip-3a), Ifng, Il1a, Il1b, Il2, Il6, Il12a, Il12b, Il17a, Il22, Il23a, Ptgs2 (Cox2), Tlr4, Tnf, Vegfa
Anti-inflammatory Genes
Il4, Il10, Il13, Tgfb1
Enzymatic Modulators of Inflammation & Immunity
Aicda (Aid), Aicda (Aid), Gzma, Gzmb, Ido1 (Ido), Ido1 (Ido), Nos2 (iNos), Ptgs2 (Cox2)
Antigen Presentation
H2-D1, H2-K1
Chemokines
Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl4 (Mip-1b), Ccl5 (Rantes), Ccl20 (Mip-3a), Ccl22 (Mdc), Ccl28, Cxcl1 (Gro1), Cxcl2 (Gro2), Cxcl5 (ENA-78, LIX), Cxcl9 (Mig), Cxcl10 (Inp10), Cxcl11 (Itac, Ip9), Cxcl11 (Itac, Ip9), Cxcl11 (Itac, Ip9), Cxcl12
Interleukins
Il1a, Il1b, Il2, Il4, Il5, Il6, Il10, Il12a, Il12b, Il13, Il15, Il17a, Il22, Il23a
Chemokine & Interleukin Receptors
Ackr3, Ccr1, Ccr2, Ccr4, Ccr5, Ccr7, Ccr9, Ccr10, Cxcr1, Cxcr2, Cxcr3, Cxcr4, Cxcr5, Il1r1
Other Cytokines
Kitl (Scf), Mif, Spp1, Tnf, Tnfsf10 (Trail)
Growth Factors & Receptors
Csf1 (Mcsf), Csf2 (GMCSF), Csf3 (Gcsf), Egf, Egfr, Igf1, Tgfb1, Vegfa
Signal Transduction
Interferon Signaling
Gbp2b, Ifng, Il6, Irf1
Interferon-Responsive Genes
Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl5 (Rantes), Cxcl9 (Mig), Cxcl10 (Inp10), Gbp2b, Irf1, Myd88, Stat1, Tlr3, Tnfsf10 (Trail)
NFκB Targets
Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl5 (Rantes), Csf1 (Mcsf), Csf2 (GMCSF), Csf3 (Gcsf), Ifng, Tnf
STAT Targets
Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl4 (Mip-1b), Ccl5 (Rantes), Csf1 (Mcsf), Csf2 (GMCSF), Csf3 (Gcsf), Cxcl9 (Mig), Cxcl10 (Inp10), Cxcl11 (Itac, Ip9), Cxcl11 (Itac, Ip9), Cxcl11 (Itac, Ip9), Cxcl12, Il1b, Il6, Il10, Il17a, Il23a, Myc
Toll-Like Receptor Signaling
Myd88, Tlr2, Tlr3, Tlr4, Tlr7, Tlr9
Transcription Factors
Foxp3, Hif1a, Irf1, Myc, Nfkb1, Stat1, Stat3, Trp53 (p53)
Apoptosis
Pro-Apoptotic
Fasl, Tnf, Tnfsf10 (Trail), Trp53 (p53)
Anti-Apoptotic
Bcl2, Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Myc, Stat3