Target List
Autophagy Machinery Components
Autophagic Vacuole Formation
Atg12Atg4aAtg4bAtg5Atg16Atg6 (BECN1)Atg8a (GABARAP)Atg8b (GABARAPL1)Atg9 (ATG9A)ema (CLEC16A)Hmt-1 (ABCB6)
Vacuole Targeting
Atg4aAtg4bAtg8a (GABARAP)Atg8b (GABARAPL1)
Protein Transport
Atg10Atg3Atg4aAtg4bAtg7Atg16Atg8a (GABARAP)Atg8b (GABARAPL1)Atg9 (ATG9A)Dlc90F (DYNLT1)
Autophagosome-Lysosome Linkage
Lamp1Atg8a (GABARAP)Atg8b (GABARAPL1)cac (CACNA1A)Ccz1CG4025 (DRAM2)comtLerpNpc1a (NPC1)NPC1b (NPC1)
Ubiquitination
Atg3Atg7HDAC6DJ-1alpha (PARK7)dj-1beta (PARK7)park (PARK2)
Proteases
Atg4aAtg4bscnyUba1
Other Autophagy Machinery Components
Atg1 (ULK2)Atg101Atg13Atg14Atg17Atg18aAtg18bAtg2 (ATG2B)
Regulation of Autophagy
Co-Regulators of Autophagy & Apoptosis
Akt1appAtg12Atg5cln3FaddfashttMtorPtenAcn (ACIN1)AMPKalpha (PRKAA1, PRKAA2)Atg6 (BECN1)BI-1Bruce (BIRC6)bsk (MAPK8)BuffyCG4025 (DRAM2)CtsB1 (CTSB)Dcp-1 (CASP7)debcl (BOK)IP3K2 (ITPKA)p53 (TP53)park (PARK2)Pi3K59F (PIK3C3)Pi3K92E (PIK3CB)sesB (SLC25A4)
Co-Regulators of Autophagy & the Cell Cycle
Ptenp53 (TP53)Rbf (RBL2)Rbf2
Autophagy Induction by Intracellular Pathogens
Lamp1
Autophagy in Response to Other Intracellular Signals
UvragBI-1cathD (CTSD)CG1598 (ASNA1)CG4025 (DRAM2)desat1 (SCD5)drpr (MEGF11)eIF4G (EIF4G1)Hrs (HGS)kibra (WWC1)p38a (MAPK14)p38b (MAPK11)pcm (XRN1)Pi3K59F (PIK3C3)Pi3K92E (PIK3CB)S6k (RPS6KB1)Vps13 (VPS13A)Vps16A (VPS16)Vps28Vps35Vps39
Chaperone-Mediated Autophagy
Hsc70-1 (HSPA8)Hsp83 (HSP90AB1)
Other Autophagy Regulatory Gene
Atg1 (ULK2)Atg101Atg13Atg14Atg17Atg18aAtg18bAtg2 (ATG2B)
Other Autophagy Genes
Act5C (ACTA2)ctpPink1Psn (PSEN1)