Target List
Up-Regulated During Epithelial-to-Mesenchymal Transition
AHNAKBMP1CALD1CDH2COL1A2COL3A1COL5A2FN1FOXC2GNG11GSCIGFBP4ITGA5ITGAVMMP2MMP3MMP9MSNSERPINE1 (PAI-1)SNAI1 (SNAIL)SNAI2SNAI3SOX10SPARCSTEAP1TCF4TIMP1LOC612942 (TMEFF1)TMEM132ATWIST1VCANVIMVPS13AWNT5AWNT5B
Down-Regulated During Epithelial-to-Mesenchymal Transition
CDH1DSPLOC488818 (FGFBP1)IL1RNKRT19MITFMST1RNUDT13OCLNRGS2SPP1TFPI2TSPAN13
Differentiation & Development
AKT1BMP1BMP2BMP7COL3A1COL5A2CTNNB1DSPERBB3F11RFOXC2FZD7GSCJAG1KRT14MITFMST1RNODALNOTCH1PTP4A1SMAD2SNAI1 (SNAIL)SNAI2SOX10TGFB2TGFB3LOC612942 (TMEFF1)TWIST1VCANWNT11WNT5AWNT5B
Cell Morphogenesis
CTNNB1FOXC2JAG1RAC1SMAD2SNAI1 (SNAIL)SOX10TGFB1TGFB2TGFB3TWIST1WNT11WNT5A
Cell Growth & Proliferation
AKT1BMP1BMP7CTNNB1EGFRERBB3LOC488818 (FGFBP1)FOXC2IGFBP4ILKJAG1MST1RNODALPDGFRBTGFB1TGFB2TGFB3TIMP1VCANZEB1
Cell Migration & Motility
CALD1EGFRFN1ITGB1JAG1MSNMST1RNODALPDGFRBRAC1STAT3TGFB1VIM
Cytoskeleton Regulators
KRT7MAP1BPLEK2RAC1VIM
Extracellular Matrix (ECM) & Cell Adhesion Molecules
BMP1BMP7CDH1CDH2COL1A2COL3A1COL5A2CTGFCTNNB1DSC2EGFRERBB3F11RFN1FOXC2ILKITGA5ITGAVITGB1MMP2MMP3MMP9PTK2RAC1SERPINE1 (PAI-1)SPP1TGFB1TGFB2TIMP1VCAN
Signal Transduction
Estrogen Receptor Signaling
ESR1KRT19TGFB3
G-Protein Coupled Receptor Signaling
AKT1FZD7GNG11RAC1RGS2
Integrin-Mediated Signaling
COL3A1CTGFILKITGA5ITGAVITGB1PTK2
Notch Signaling
FOXC2JAG1NOTCH1
Receptor Tyrosine Kinase Signaling
EGFRERBB3PDGFRBRGS2SPARC
TGFβ / BMP Signaling
BMP1BMP2BMP7COL3A1SMAD2TGFB1TGFB2TGFB3
WNT Signaling
CTNNB1FZD7GSK3BWNT11WNT5AWNT5B
Transcription Factors
CTNNB1ESR1FOXC2GSCNOTCH1GEMIN2MITFSMAD2SNAI2SNAI3SOX10STAT3TCF3TCF4TCF7L1TWIST1ZEB1ZEB2