Target List
NFκB Signaling
NFκB Signaling Ligands & Receptors
CARD10CD40 (TNFRSF5)EGFRF2RFASLG (TNFSF6)IL10IL1BIL1R1CXCL8NOD1 (CARD4)TLR1ATLR2ATLR3TLR4TNFRSF1ATNFRSF1BTNFRSF10BTNFSF10 (TRAIL)
Signaling Downstream of NFκB
BIRC2 (c-IAP-2)FADDIRAK2IRF1MYD88RIPK1RIPK2TBK1TICAM1 (TRIF)TNFAIP3TOLLIPTRADDTRAF2TRAF3TRAF5TRAF6
Cytoplasmic Sequestering / Releasing of NFκB
CHUK (IKKα)IKBKBIKBKENFKBIA (IκBα, MAD3)NFKBIBNFKBIE
Transcription Factors
ATF2CREBBPNFKB1NFKB2RELRELARELBSMAD3
NFκB Responsive Genes
Immune Response
CCL20 (MIP-3A)CCL5 (RANTES)CD83CSF1 (MCSF)CSF2 (GM-CSF)CSF3 (GCSF)CXCL8IFNA3IFNG
Apoptosis
AGTBCL2A1BCL2L1 (BCLXL)LITAF (TNF)PCASP1
Other Factors Involved in NFκB Pathway
Kinases
AKT1EIF2AK2MAPK1 (ERK2)MAP3K1RAF1ZAP70
Transcription Factors
ATF1EGR1FOSJUNSTAT1
Other NFκB Signaling Genes
BCL10CARD11CASP1 (ICE)CASP8 (FLICE)CFLARHMOX1LITAF (TNF)PSIP1RHOASLC20A1STX11TIFATNFAIP2