Target List
Embryonic Stem Cell (ESC) Specific Genes
Embryonic Stem Cell Markers​
ALPL, GDF3 (VGR-2), TDGF1, TERT
Chromatin Modification Enzymes & Remodeling Factors​
CHD1, CHD7, KAT5
Transcriptional Regulation​
CNOT3, NR0B1, PAF1, TRIM28
Transcription Factors​
ESRRB, KLF4, LIN28A, MYC, NANOG, POU5F1 (OCT4), PRDM14, SALL4, SMAD1 (MADH1), SMAD2 (MADH2), SMAD3 (MADH3), SOX2, STAT3, TBX3, TCF3, THAP11, UTF1, ZFX
Pluripotency
AICDA (AID), AICDA (AID), CCNA2, CDC42, CDK1, DPPA2, DPPA3, DPPA4, DPPA5, FGF2 (BFGF), HSPA9, MYBL2, NR5A2, NR6A1, OTX2, RIF1, SCN1A, SOX15, TCL1A, ZFP42
Induced Pluripotent Stem Cell Enhancers
AICDA (AID), AICDA (AID), KLF4, LIN28A, MYC, NANOG, POU5F1 (OCT4), SOX2, UTF1
Germ Layers
Ectoderm​
EN2, FGF5, MEIS1, NCAM1, PAX6
Mesoderm​
DES, HAND1, MESP1, MIXL1, MYOD1, TBXT (Brachyury)
Endoderm​
GATA1, GATA6, GSC, HNF4A, SOX17, SOX7
Progenitors & Multi-Potent Stem Cells
Neural Progenitors​
GFAP, NES, OLIG2, SOX3
Cardiac Progenitors​
ISL1, NKX2-5
Early Smooth Muscle Cells​
ACTA2 (α-SMA), TAGLN
Hematopoietic Stem Cells & Early Endothelial Cells​
ETV2, FLII, GATA2, TAL1, TEK (TIE-2, TIE2)
Mesenchymal Stem Cells​
CD44, ENG (EVI-1), NT5E, THY1
Preadipocytes​
ALB, TAT