GeneGlobe ID: PAHS-131Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human Breast Cancer

RT2 Profiler PCR Array
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Product Specification

Target List
Breast Cancer Classification Markers
Luminal A-C Breast Cancers​
ESR1 (ERα), FOXA1, GATA3, KRT8, KRT18, SLC39A6, TFF3, XBP1
HER2-Like Breast Cancers​
ERBB2 (HER-2, NEU), GRB7
Basal-Like / Triple Negative Breast Cancers​
BIRC5, EGFR (ERBB1), KRT5, NOTCH1
Breast Cancer Metastasis to Lung​
ID1, MMP2, PTGS2 (COX2)
Signal Transduction
Steroid Receptor-Mediated Signaling​
AR, BRCA1, CCNE1, CTNNB1, ESR1 (ERα), ESR2 (ERβ), IGF1, KRT19, PGR, RB1
Hedgehog Signaling​
BCL2, CCND1, GLI1, SNAI2
Glucocorticoid Signaling​
IGFBP3, NME1 (NM23), NR3C1 (GRL)
Classical WNT Signaling​
APC, CCND1, CTNNB1, SFRP1
AKT & PI3 Kinase Signaling​
AKT1, ERBB2 (HER-2, NEU), IGF1, IGF1R, PTEN
Notch Signaling​
BIRC5, NOTCH1
MAP Kinase Signaling​
MAPK1 (ERK2), MAPK3 (ERK1), MAPK8 (JNK1), TP73
Epithelial-to-Mesenchymal Transition (EMT)
CTNNB1, NOTCH1, SRC, TGFB1, TWIST1
Angiogenesis
CDH13, CTNNB1, EGF, ERBB2 (HER-2, NEU), ID1, IL6, JUN, NOTCH1, PLAU (UPA), PTEN, SERPINE1 (PAI-1), SLIT2, THBS1 (TSP-1), VEGFA
Cell Adhesion Molecules
ADAM23, APC, BCL2, CDH1 (E-Cadherin), CDH13, CDKN2A (P16INK4A), CSF1 (MCSF), CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), PTEN, TGFB1, THBS1 (TSP-1)
Proteases
ADAM23, CST6, CTSD, MMP2, MMP9, PLAU (UPA), PYCARD (TMS1, ASC)
Apoptosis
AKT1, APC, BAD, BCL2, CDH1 (E-Cadherin), CDKN1A (p21CIP1, WAF1), CDKN2A (P16INK4A), GSTP1, IGF1, IL6, JUN, MUC1 (mucin), NME1 (NM23), RARB, SFN (14-3-3σ, YWHAS), SFRP1, TP53 (p53), TP73, TWIST1
Cell Cycle
APC, BCL2, CCNA1, CCND1, CCND2, CCNE1, CDK2, CDKN1A (p21CIP1, WAF1), CDKN1C (p57Kip2), CDKN2A (P16INK4A), JUN, MKI67, MYC, PTEN, RASSF1, RB1, SFN (14-3-3σ, YWHAS), TP53 (p53)
DNA Damage & Repair
APC, ATM, BRCA1, BRCA2, CCND1, CDKN1A (p21CIP1, WAF1), MAPK1 (ERK2), MGMT (AGT), MLH1, SFN (14-3-3σ, YWHAS), TP53 (p53), TP73
Xenobiotic Transport
ABCB1 (MDR1, PGY1), ABCG2 (BCRP)
Transcription Factors
AR, CTNNB1, ESR1 (ERα), ESR2 (ERβ), FOXA1, GATA3, HIC1, JUN, MYC, NOTCH1, NR3C1 (GRL), PGR, PRDM2 (RIZ1), RARB, RB1, TP53 (p53), TP73, XBP1
Gene Resource List
Array Layout for PCR Plates
File Size: 139.24 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 133.6 KBLanguage: English

Resources

Brochures & Guides (3)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Download Files (3)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Poster for download
Kit Handbooks (1)
For pathway-focused gene expression profiling using real-time RT-PCR
Instrument Technical Documents (2)
For gene expression and genomic analysis
For pathway-focused gene expression analysis
Certificates of Analysis (1)
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