Target List
Cell Surface Receptors
Cadherins​
CDH1 (E-Cadherin), CDH2 (N-Cadherin), CDH3, CDH4, CDH5
Desmocollins & Desmogleins​
DSC1, DSC2, DSC3, DSG1, DSG2, DSG3, DSG4
Nectins​
NECTIN1, NECTIN2, NECTIN3, NECTIN4
Notch Signaling​
DLL1 (DELTA1), NOTCH1, NOTCH2, NOTCH3, NOTCH4
Desmosomes
CDSN, DSP, JUP (CTNNG), PKP1, PKP2, PKP3, PKP4, PNN, PPL
Junction Associated Proteins
AJAP1, CTNND1, DLG5, AFDN, PARD3, P2RX6, PERP, TJP1, VEZT
Catenins
ARVCF, CTNNA1, CTNNA2, CTNNA3, CTNNB1, CTNND1
Cytoskeleton Regulators
ACTN1, ACTN2, ACTN3, ACTN4, ANAPC1, BAIAP2, CDC27, EXOC2, FARP2, FLNA, FLNB, LMO7, MAPRE1, MAPRE2, NME1 (NM23), PARD3, SORBS1, SSX2IP, TLN1, TLN2, VCL, WAS, WASF1, WASL, ZYX
Endocytosis
DNM1, DNM2, HGS, LMO7, PIK3CG, PLPP3, SORBS1
Protein Kinase Signaling
CSNK2A1, CSNK2A2, CSNK2B, DLG5
G-Protein Signaling
ARF6, CDC42, DOCK4, FARP2, IQGAP1, AFDN, RAC1, RALA, RHOA
Ubiquitin-Protein Ligases (E3)
ANAPC1, CBLL1