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GeneGlobe ID: PAHS-3012Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human Apoptosis 384HT

RT2 Profiler PCR Array

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Product Specification

Target List

Caspases & Regulators
Caspases​
CARD17CARD18CASP1 (ICE)CASP10 (MCH4)CASP14CASP2CASP3CASP4CASP5CASP6CASP7CASP8 (FLICE)CASP9CFLAR (CASPER)CRADDMALT1PYCARD (TMS1, ASC)COP1
Caspase Activation​
AIFM3APAF1BAXBBC3 (PUMA)BCL2L10BCL2L13CASP1 (ICE)CASP8AP2CASP9COL4A3CYCSDIABLOEIF2AK3F2 (Thrombin)F2R (PAR1)FOXL2HIP1HSPE1IFNB1IFT57LCKMAP3K5MOAP1MTCH1MYCNLRC4 (IPAF)NLRP1NLRP12NLRP2NLRP3NOD1 (CARD4)PMAIP1 (NOXA)PYCARD (TMS1, ASC)STAT1TNFRSF10A (TRAIL-R)TNFRSF10B (DR5)TNFSF15TP53 (p53)TPD52L1VCP
Caspase Inhibition​
BIRC5CD27 (TNFRSF7)DHCR24IFI6LAMTOR5SFN (14-3-3σ, YWHAS)TNFAIP8TNFSF14TRIAP1XIAP
Anti-Apoptotic
Positive Regulation of Anti-Apoptosis​
BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BRECD28ERC1MAPK8IP2 (JIP-1)OPA1PRKAA1 (AMPK)RASA1
Negative Regulation of Anti-Apoptosis​
PIK3R2 (p85-BETA)RTN4TNFAIP8
Other Anti-Apoptotic Genes​
AATFAKT1ALOX12ANXA1ANXA4API5ATF5AVENAZU1BAG1BAG3BAG4BCL2BCL2A1 (BFL1)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L10BCL2L2BDNFBECN1BFARBIRC2 (c-IAP1)BIRC3 (c-IAP2)BIRC5BIRC6BIRC7BIRC8BNIP1BNIP2BNIP3BRAFCASP2CBX4CCL2 (MCP-1)CD27 (TNFRSF7)CD40LGCEBPBCFDP1CFL1CFLAR (CASPER)CRYAACRYABDAD1DDAH2DHCR24EEF1A2FAIMFAIM2FASFOXO1GDNFGFRALGLO1GSTP1HDAC1HDAC3HIPK3HMGB1HSP90B1HSPA1BHSPA9HSPB1 (HSP27)HTATIP2HTTIER3IFI6IGF1RIL10IL1AIL2IL31RALAMTOR5MALT1MCL1MKL1MPOTESMINMYBL2MYO18ANAIPNFKB1NME5NOL3NOTCH2NPM1NRG2NTF3PAK7PAX7PEA15PIK3CA (p110-alpha)PIM2POGKPOLBPRDX2PRKCZPRLRPROK2PSEN1RELARNF7SEMA4DSERPINB2 (PAI-2)SERPINB9SFRP1SH3GLB1SNCASOCS2SOCS3SONSPHK1SPP1STAMBPTAX1BP1TBX3TGFB1TIAF1TMX1TNFTNFAIP3TNFAIP8TNFRSF10DTNFRSF18TNFRSF6BTNFSF18TPT1TRIAP1TSC22D3VEGFAVHLXIAPYWHAZZC3HC1
Induction of Apoptosis
Induction of Apoptosis by Death Domain Receptors​
BIDCRADDDAXXDEDD2FADDIL18TNFTNFRSF10B (DR5)
Induction of Apoptosis by DNA Damage​
ABL1AIFM1BCL3BRCA1CHEK2 (RAD53)CIDEACIDEBDYRK2IFI16MBD4MSH6PCBP4PMLSFN (14-3-3σ, YWHAS)TP53 (p53)TP73
Induction of Apoptosis by Oxidative Stress​
GPX1PRODHRNF7TP53I3 (PIG3)
Induction of Apoptosis by Extracellular Signals​
ADORA1BTKCASP8AP2CD28CD38CD5CFLAR (CASPER)DAPDAP3DAPK1DPF2FASTKMAP3K5NDUFA13PDCD6PRKCARIPK3SPNTIMP3TNFRSF25 (DR3)
Induction of Apoptosis by Intracellular Signals​
CDKN1A (p21CIP1, WAF1)CUL1CUL2CUL3CUL4ACUL5HIPK2MYCSART1
Other Pro-Apoptotic Genes​
ACVR1BAIFM2AIFM3ALOX15BAPOEBADBAK1BAXBBC3 (PUMA)BCL10BCL2L11BCL2L13BCLAF1BIKBNIP1BNIP3BNIP3LBOKCASP10 (MCH4)CASP3CASP4CASP6CD2CD27 (TNFRSF7)CD70CEBPBCIDECCOL4A3DAPK2DAPK3DCCDDX20DEDDDIABLOEI24ERCC2 (XPD)ERCC3 (XPB)ERN1ERN2FASFASLG (TNFSF6)FEM1BFOXL2FOXO3HRKHTATIP2IFNA2IFNB1IFNGIKBIPIKBKGIL19INHAINHBAJMYLALBALCKLTA (TNFB)MALMAP3K10MAPK1 (ERK2)MX1NDUFS3NGFRNLRP1NLRP3NME3NOTCH2NOX5NUDT2NUPR1PDCD5PLAGL1PLAGL2PLEKHF1PLGPMAIP1 (NOXA)PPP1R13BPPP2CAPPP2R1APPP2R1BPRKCEPRKRAPRUNE2PTENPTHPYCARD (TMS1, ASC)RPS3ARUNX3S100BSAP30BPSERINC3SIPA1SMNDC1SSTSSTR3STK17ASTK17BTBX5TIA1TIAL1TLR2TNFRSF10A (TRAIL-R)TNFRSF19TNFRSF9TNFSF10 (TRAIL)TNFSF14TNFSF8TP53BP2TP63TPD52L1TRADDTRAF3TRAIPUNC13BUTP11LZNF443
TNF Domain Proteins
EDAFASLG (TNFSF6)LTA (TNFB)LTBTNFTNFSF10 (TRAIL)TNFSF14TNFSF15TNFSF8
TNFR Domain Proteins
CD27 (TNFRSF7)CD40 (TNFRSF5)FASLTBRNGFRTNFRSF10A (TRAIL-R)TNFRSF10B (DR5)TNFRSF10DTNFRSF18TNFRSF19TNFRSF1A (TNFR1)TNFRSF1BTNFRSF21TNFRSF25 (DR3)TNFRSF6BTNFRSF8TNFRSF9
BCL2 & BAG Domain Proteins
BAG1BAG3BAG4BAXBCL2BCL2A1 (BFL1)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L10BCL2L13BCL2L2MCL1
BIR Domain Proteins
BIRC2 (c-IAP1)BIRC3 (c-IAP2)BIRC5BIRC6BIRC7BIRC8NAIPXIAP
CARD Domain Proteins
APAF1BCL10BIRC2 (c-IAP1)BIRC3 (c-IAP2)CARD10CARD11CARD14CARD17CARD18CARD6CARD9CASP1 (ICE)CASP2CASP4CASP5CASP9CRADDNLRP1NOD1 (CARD4)NOD2NOL3PYCARD (TMS1, ASC)COP1RIPK2
Death Domain Receptors
CRADDDAPK1EDARFADDMALT1NFKB1NFKB2NGFRPIDD1 (PIDD)RIPK1TNFRSF10A (TRAIL-R)TNFRSF10B (DR5)TNFRSF1A (TNFR1)TNFRSF21TNFRSF25 (DR3)TRADD
TRAF Domain Proteins
TRAF2TRAF3TRAF5TRAF7
Other Apoptosis Regulators
BCL6CEBPGDBPDDIT3 (GADD153, CHOP)GRM4LGALS1MADDMAPK8 (JNK1)NKX3-2POU4F1PROP1RARGSTAT5ASTAT5BTBK1TDGF1TRAF6MAP3K20

Product Resources

Gene Table for 384-well Array
File Size: 181.78 KBLanguage: English

Resources

Supplementary Protocols (10)
ABI 7500 & ABI 7500 FAST (Software Version 2.0.4) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (388KB)
ABI 7900HT (for SDS Software 2.1, 2.3 and 2.4) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (320KB)
ABI StepOnePlus (for Software Version 2.0) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (77KB)
Bio-Rad CFX96 and CFX384 instrument setup instructions for RT2 Profiler PCR Arrays
PDF (298KB)
Bio-Rad iCycler & iQ Real-Time PCR Systems (for Software Version 3.1) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (249KB)
Eppendorf Mastercycler ep realplex instrument setup instructions for RT2 Profiler PCR Arrays
PDF (554KB)
Stratagene Mx3000P qPCR System real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (259KB)
Rotor-Gene Q real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (175KB)
Roche LightCycler 480 real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (1MB)
Life Technologies ViiA7 (ViiA 7 Software v1.2) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (511KB)
Brochures & Guides (3)
RT2 Profiler PCR Arrays: Pathway Analysis - (EN)
PDF (1MB)
Total RNA Discovery - (EN)
PDF (255KB)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Technical Guide to QIAGEN PCR Arrays
PDF (2MB)
Safety Data Sheets (1)
Safety Data Sheets
Articles (17)
(EN) Control of PPARγ and mTOR in insulin resistance
(EN) miRNA regulation of angiogenesis: new roles for IGF-1R signaling and heparin
(EN) Regulation of BAX mediated apoptosis by BCL2 family members
(EN) Chemokines: manipulators of metastasis
(EN) DNA damage repair — regulation through autophagy
(EN) Silencing cell-cell communication to combat drug toxicity
(EN) Cellular stress, TGF-β, and EMT: what are the true origins of fibrosis?
(EN) The role of inflammation in cancer
(EN) What enhances the inflammatory response: new players and unexpected roles
(EN) Induced pluripotent stem cells: real stem cells?
(EN) Lipid autophagy in obesity and atherosclerosis: chewing the fat
(EN)Metabolic homeostasis: regulation of FOXO by class IIa HDACs
(EN)Regulation of the extracellular matrix by miRNA: impact on cancer metastases
(EN)Inflammation and neurodegenerative disease: a role for the estrogen receptor in suppression of inflammation in the brain
(EN)A good transcription factor gone rogue: the two faces of NRF2 in oxidative stress
(EN)Managing mortality: how cells regulate telomerase activity
(EN) Master Regulators Direct TGF-beta and Smad Signaling in Different Cell Types
Download Files (3)
Housekeeping Gene Data Analysis
XLSX (60KB)
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

RT2 Profiler PCR Array Data Analysis v3.5 Handbook
PDF (770KB)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Scientific Posters (1)
Explore the RNA Universe!
PDF (1MB)
Poster for download
Kit Handbooks (1)
RT2 Profiler PCR Array Handbook
PDF (702KB)
For pathway-focused gene expression profiling using real-time RT-PCR
Performance Data (7)
PCR_Array_4x96_384-Well_Conversion Spreadsheet
XLSX (38KB)
RT2 Profiler Housekeeping Genes PCR Array Data Analysis 1808
XLSX (65KB)
RT2 Profiler PCR Array 384HT Data Analysis Spreadsheet 1808
XLSX (1MB)
RT2 Profiler PCR Array Data Analysis Spreadsheet 1904
XLSX (3MB)
RT2 Profiler RNA QC PCR Array Data Analysis Spreadsheet 1808
XLSX (60KB)
RT2 qPCR Assay Data Analysis 1808 Spreadsheet
XLSX (104KB)
Universal Custom PCR Array Conversion
XLSX (291KB)
Instrument Technical Documents (2)
(EN) - RT2 Profiler PCR Arrays
PDF (431KB)
For pathway-focused gene expression analysis
QIAGEN Service Core - (EN)
PDF (333KB)
For gene expression and genomic analysis
White Papers (2)
RT2 Profiler PCR Arrays: Pathway-focused gene expression profiling with qRT-PCR
PDF (1MB)
RT2 Profiler PCR Array application examples
PDF (563KB)
Gene Expression Analysis (1)
(EN) Wnt Signaling: GSK3 Inhibition Through Sequestration in Multivesicular Bodies
Certificates of Analysis (1)
Certificates of Analysis
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Introducing the RT² Profiler™ PCR Array Human Apoptosis 384HT, a cutting-edge addition to our RT2 Profiler PCR Arrays lineup, specifically designed for Real-Time PCR applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the RT² Profiler™ PCR Array Human Apoptosis 384HT facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting Real-Time PCR, or any other sophisticated analyses, this product from our RT2 Profiler PCR Arrays collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with RT² Profiler™ PCR Array Human Apoptosis 384HT and elevate your work to new heights.
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