Target List
Experimentally Verified let-7a Target Genes
BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BSG, CASP3, CCNA2, CCND1, CCND2, CDC25A, CDC34, CDK6, CLOCK, COL1A2, DICER1, E2F1, E2F2, AGO4, HOXA9, IFNB1, IGF2BP1, IL13, IL6, ITGB3, KLK10, KLK6, KRAS, LIN28A, MAPK14 (p38ALPHA), MYC, MYCN, NCOA3, NF2, NKIRAS2, NR2E1, NRAS, PRDM1, RAVER2, SALL4, SLC11A2, SOCS4, TGFBR1 (ALK5), TLR4, TRIM71, TUSC2, UHRF2, WNT1
Bioinformatically Predicted let-7a Target Genes
ACVR1B, ADAMTS8, BZW1, CCP110, CEP135, CHD4, COL3A1, COL5A2, DDX19B, DUSP1 (PTPN16), FRMD4B, GATM, GDF6, GNPTAB, HIF1AN, HIP1, IGF2BP3, ELP1, IQCB1, LRIG2, LRIG3, MAP4K3, MAPK6 (ERK3), MAPK8 (JNK1), NPHP3, PARM1, PBX3, PDPR, PLA2G3, PLXNC1, PPP2R2A, RANBP2, RASGRF2, RCN1, SMC1A, USP12, USP32, WDR37, ZBTB5, ZFYVE26