Target List
EGFR Signaling
Bcar1CblEgfEgfrEps8Erbb2Gab1Grb2HbegfNck2Nup62Shc1
Platelet-Derived Growth Factor Receptor Signaling
Bcar1PdgfaPdgfbPdgfraPlat
Intracellular Signaling
AKT Signaling
Akt1Akt2Akt3BadLOC100689370 (Casp9)Chuk (Ikkα)Faslg (Tnfsf6)Foxo3Nfkb1 (Nfkb1)Pten
ERK1 / ERK2 Signaling
EgfrElk1Grb2Map2k1Mapk1 (Erk2)Mapk3Mknk1PdgfraRaf1Shc1SrcStat3
IκB Kinase / NFκB Cascade
Chuk (Ikkα)Faslg (Tnfsf6)Gsk3aGsk3bNup62RhoaStat1
JAK / STAT Signaling
Eps8Gab1Grb2Jak1Nup62Ppp2caSrcStat1Stat3Stat5a
JNK / p38 Signaling
Map2k4Map3k2Mapk10Mapk8Mapk9
MAP Kinase Signaling
Dusp1 (Ptpn16)Dusp6EgfEgfrMap2k1Map2k7Mapk1 (Erk2)Mapk10Mapk3Mapk8Mapk9Ppp2caPrkcaShc1
PI3 Kinase Signaling
Pik3ca (p110alpha)Pik3r1Pik3r2Pten
G-Protein Signaling
Grb2HrasNrasNup62Rap1aRasa1Rhoa
Other Intracellular Signaling Molecules
ArafBrafCblCsnk2a1Csnk2bIkbkbNck2Pdpk1Plcg1Rps6kb1
Cell Survival & Growth
Apoptosis
Akt1BadBcar1Bcl2BrafCasp3LOC100689370 (Casp9)Faslg (Tnfsf6)Foxo3Il2Lta (Tnfb)Mapk1 (Erk2)Nfkb1 (Nfkb1)Nup62Pik3r2Ppp2caPrkcaPtenRaf1Rasa1Stat1Tp53 (p53)
Cell Cycle
Bcl2Ccnd1Dusp1 (Ptpn16)Dusp6EgfrHrasKrasMapk1 (Erk2)Mapk3NrasPdgfaPdgfbPpp2caPrkcaPtenRap1aShc1Stat1Tp53 (p53)
Cell Differentiation
Foxo3Il2Ppp2caTp53 (p53)
Cell Growth
Bcar1Ccnd1EgfHbegfIl2PdgfaPdgfbPdgfraPpp2caRasa1Shc1Tp53 (p53)
Cell Motility
Actr2Bcar1EgfrFn1HbegfMap2k1Mapk8PtenStat3
Cell Proliferation
Bcar1Bcl2EgfEgfrEps8Gab1HbegfIl2Nck2Nup62PdgfaPdgfbPdgfraPtenRaf1Shc1Tp53 (p53)
Metabolism
DNA Metabolism
Atf1Atf2 (Creb2)Creb1EgfEgfrFosNup62Ppp2caTp53 (p53)
Lipid Metabolism
ArafBrafPik3r1Plcg1Ppp2caPrkcaPtenRaf1Shc1
Protein Metabolism
Actr2Akt1Akt2Akt3ArafAtf1Atf2 (Creb2)BrafCblChuk (Ikkα)Creb1Csnk2a1Dusp1 (Ptpn16)Dusp6EgfrFosGsk3aGsk3bIkbkbJak1Map2k1Map2k4Map2k7Map3k2Mapk1 (Erk2)Mapk10Mapk3Mapk8Mapk9Mknk1PdgfraPdpk1Ppp2caPrkcaPtenRaf1Rps6kb1Src
Other Metabolism Genes
Col1a1Eif4eFn1Mmp7Rasa1
Development
BrafCol1a1HbegfPtenRasa1Stat3
Stimulus Response
Response to Wounding
Bcar1Bcl2Fn1HbegfIl2Nck2Nfkb1 (Nfkb1)PdgfbStat3
Response to Other Stimuli
Akt1Chuk (Ikkα)Col1a1Dusp1 (Ptpn16)EgfrFaslg (Tnfsf6)FosKrasLta (Tnfb)Map2k1Map2k7Mapk1 (Erk2)Mapk8Mapk9Nfatc3Ppp2caStat1Stat5aTp53 (p53)
Transcription Factors & Regulators
Akt1Atf1Atf2 (Creb2)CblCreb1Egr1Eif4eElk1FosFoxo3IkbkbJunMknk1Nfatc3Nfkb1 (Nfkb1)Nup62Ppp2caStat1Stat3Stat5aTp53 (p53)
Actin & Calcium Ion Homeostasis
Actr2Bcar1CblEgfEgfrMmp7Nck2Pdpk1Plcg1PrkcaRasa1RhoaStat1Stat3Stat5a