Target List
Necrosis
Regulation of Necrosis
FasFaslg (Tnfsf6)Ripk1Slc25a4Tnf
TNF-Induced Necrosis
Atp6v1g2BmfCcdc103Commd4CyldDefb1Dennd4aDpysl4Eif5bFoxi1Galnt5Grb2Hspbap1Jph3Kcnip1LOC103161439 (Mag)Parp2Rab25Spata2Sycp2Tmem57Txnl4b
Other Necrosis Genes
Cd40 (Tnfrsf5)FaddMgea5MpgRipk1Ripk3PalmParp1 (Adprt1)Sp1Tmem123
Potential Necrosis Genes
RIPK1 Interactors
FusNfkb1 (Nfkb1)Ripk2Ripk3
RIPK3 Interactors
Glud1GlulLOC100753288 (Pygl)Phtf2Ripk1
PARP1 Interactors
Capn1Capn2Capn3Capn5Capn6Capn7Capns1
Death Domain Receptors
FasTnfrsf1a (Tnfr1)
Death Receptor Signaling
BidBirc3 (c-Iap2)Casp8ap2CyldEda2rFaddFaf1Fem1bIkbkgMaddMyd88NgfNgfrNgfrap1Parp1 (Adprt1)PiddRipk1Tnfrsf14Tnfrsf17Tnfrsf1bTnfrsf25 (Dr3)Tnfrsf4 (Ox40)Tnfrsf8Tnfsf15TraddTraf2Traf5
Apoptosis
Pro-Apoptotic
Aifm1BaxBidBmfBnip3lCasp8ap2FaddFaf1FasFaslg (Tnfsf6)Fem1bIkbkgMaddNgfrNgfrap1PiddRipk1Ripk2Ripk3TnfTnfrsf25 (Dr3)Tnfrsf8Tnfsf10 (Trail)TraddTraf2Traf5
Anti-Apoptotic
ArBirc3 (c-Iap2)Bnip3lCa9FasNfkb1 (Nfkb1)Myd88NgfNgfrRipk1Ripk2TnfTnfrsf1a (Tnfr1)Tnfrsf1bTnfrsf4 (Ox40)Traf2Traf5
TNF-Induced Apoptosis
Atp6v1g2CyldSpata2Sycp2
Oxidative Stress
Aifm1Glud1LOC100760802 (Cybb)LOC100766833 (Cyba)Nox1Nox4
Mitochondrial Genes
Aifm1BaxBidBnip3lGlud1GlulLOC100760802 (Cybb)LOC100766833 (Cyba)Ripk1Slc25a4