Target List
Conduction of Pain
Ion Channels
Trpa1, Trpv3, Trpv1
Sodium Channels
Scn4a, Scn8a, Scn9a, Slc6a2
Potassium Channels
Kcnj5, Kcnj10, Kcnk2, Kcnq4, Kcnip1, Kcnq2
Purinergic (P2Y) Receptors
Adora1, P2ry1, P2rx6, P2rx7
Opioid Receptors
Oprk1, Oprd1, Oprm1
Cannabinoid Receptors
Cnr2
Synaptic Transmission
Glutamate Receptors
Grin2a, Grin2b, Grm5, Grm1
Serotonin (5-Hydroxytryptamine) Receptors
Htr1b (Htr1a), Htr2a
Calcium Channels
Cacna1b
Pain Response Modulation
Eicosanoid Metabolism
Ptger3, Ptger1, Ptges2, Ptger4, Ptges, Ptges3, Ptgs1, Ptgs2 (Cox2)
Inflammation
Ace3, Alox5, Bdkrb2, Chrna4, Chrnb4, Csf1, Ednra, Faah, Il6, Itgam, Itgb2, Il18, Gch1, Cx3cr1, Mapk3, Cckbr, Il2, Cd14, Lif, Osm, Il10, Mapk1 (Erk2), Dbh, Tac3, Ccr2, Prkcg (Prkcc, Prkcg), Prkcg (Prkcc), Rtn4, Tnf, Cd4, Edn1, Tspo, Il1a, Pnoc, LOC100772276 (Calca), Cck, Penk, Il1b, Mapk14 (p38alpha), Mapk8, Tlr4
Neurotransmitters
Adrb2, Dbh, Comt, Pnoc, Penk, Adrb3, Maob
Neurotrophins
Ngf, Bdnf, Gdnf, Ntrk2