Target List
Regulation of Adipogenesis
Adipokines​
Adig, Adipoq, Cfd, Lep (Leptin), Retn
Hormones​
Agt, Angpt2
Lipases​
Lipe, Lpl
PPARÎł Targets
Adipoq, Agt, Cebpa, Cfd, Fabp4, Fasn, Irs2, Klf15, Lipe, Lpl, Pparg, Ppargc1a (Pgc-1alpha), Retn, Sirt3, Slc2a4 (Glut4), Srebf1
Adipogenesis Regulation
Pro-Adipogenesis​
Acacb, Axin1, Ccnd1, Cdk4, Cebpb, Cebpd, Dkk1, E2f1, Fabp4, Fasn, Fgf1, Fgf2 (bFGF), Irs2, Jun, Lmna, Lpl, Pparg, Rxra, Sfrp1, Sfrp5, Slc2a4 (Glut4), Wnt5b
Anti-Adipogenesis​
Adrb2, Cdkn1a (p21Cip1, Waf1), Cdkn1b (p27Kip1), Ddit3 (Gadd153, Chop), Dlk1, Foxo1, Hes1, Lrp5, Ncor2, Runx1t1, Shh, Sirt1, Sirt2, Taz, Tcf7l2, Tsc22d3, Vdr, Wnt1, Wnt3a
Pro-White Adipose Tissue​
Bmp2, Bmp4, Cebpa, Egr2, Fgf10, Klf15, Klf4, Srebf1
Anti-White Adipose Tissue​
Gata2, Gata3, Klf2, Klf3
Pro-Brown Adipose Tissue​
Bmp7, Creb1, Dio2, Foxc2, Insr, Irs1, Mapk14 (p38alpha), Nrf1, Ppara, Ppard, Ppargc1a (Pgc-1alpha), Ppargc1b, Prdm16, Sirt3, Src, Ucp1, Wnt5a
Anti-Brown Adipose Tissue​
Ncoa2, Nr0b2, Nr1h3, Rb1, Twist1, Wnt10b