Target List
Pro-Fibrotic
CCL2 (MCP-1)CTGFIL4GREM1IL21IL13RA2CCL3IL5IL13
Anti-Fibrotic
LOC100008826HGFIFNGIL10IL13RA2
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents
COL1A2
Extracellular Matrix (ECM) Remodeling Enzymes
TIMP1LOXMMP1MMP13MMP14MMP2MMP3MMP9PLAT (TPA)PLAU (UPA)PLGSERPINB2SERPINE1 (PAI-1)SERPINH1TIMP2TIMP3TIMP4
Cell Adhesion Molecules
ITGA1ITGAVITGB1ITGB5ITGB6ITGB8ITGA2
Inflammatory Cytokines & Chemokines
CCL2 (MCP-1)CCL4 (MIP-1B)CXCR4IFNGIL10IL1AIL1BIL4IL4RCCR7IL21IL13RA2CCL3IL12AILKIL5CCR2IL13TNF
Growth Factors
CTGFEDN1HGFEGFPDGFCPDGFAPDGFDVEGFA
Signal Transduction
TGFβ Superfamily Members
LOC100008826CAV1DCNENG (EVI-1)SMAD7SAR1BGREM1LTBP1SAR1ACUL1TGFBR1INHBCPRKCDSMAD2SMURF2TGFB1TGFB2TGFB3THBS1 (TSP-1)ZFYVE9
Transcription Factors
CEBPZJUNETS1FLI1NFIBSP3MYCSP1STAT1STAT6YBX1
Epithelial-to-Mesenchymal Transition (EMT)
LOC100008826COL1A2ITGAVITGB1ILKMMP2MMP3MMP9SERPINE1 (PAI-1)SKILSMAD2TGFB1TGFB2TGFB3