Target List
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents​
COL14A1, COL1A2, COL4A3, COL5A1, COL5A3, DCN, VTN
Extracellular Matrix (ECM) Remodeling Enzymes​
CTSK, F3, FGA, TIMP1, PLAUR (uPAR), MMP1, MMP2, MMP3, MMP9, PLAT (TPA), PLAU (UPA), PLG, SERPINE1 (PAI-1)
Cell Adhesion Molecules​
ITGA1, ITGA4, ITGA5, ITGA6, ITGAV, ITGB1, ITGB5, ITGB6, ITGA2, TNC
Cytoskeleton Regulators​
ACTC1, RHOG, RHOC, LOC100009332
Inflammatory Cytokines & Chemokines
CCL2 (MCP-1), CCL4 (MIP-1B), IFNG, IL10, IL1A, IL1B, IL2, IL4, IL6, CXCL8, LOC100354804 (CXCL2), CD40LG
Growth Factors
CSF2, CTGF, FGF2 (BFGF), HGF, IGF1, EGF, HBEGF (DTR), MIF, FGF10, PDGFA, INHBA, CSF3 (GCSF), PDGFB, LIF, TGFB1, TNF, VEGFA
Signal Transduction
TGFβ / BMP Signaling​
TGFBR3, INHBA, TGFB1, TGFB3, STAT3
WNT Signaling​
CTNNB1, DKK3, WISP3, WNT2, WNT5A
Kinases​
PIK3CA (p110-alpha), MAPK1 (ERK2), PTK2, MAPK3 (ERK1), PTEN
Cell Surface Receptors​
IL6ST (GP130), EGFR (ERBB1), TGFBR3, TLR4
Other Signal Transduction Genes​
PTGS1 (COX1), PLOD2, GRB2, PTGS2 (COX2), TIAM1