Target List
Autophagy Machinery Components
Autophagic Vacuole Formation
AMBRA1ATG16L1ATG4AATG4CATG4DATG5ATG9AATG9BBECN1CTSDGABARAPGABARAPL2LAMP1MAP1LC3BATG12 (ATG12)MAP1LC3AULK1 (ULK1)GABARAPL1LOC717813 (ATG4B)LOC718945 (WIPI1)PSEN1RB1CC1RGS19TM9SF1
Vacuole Targeting
ATG4AATG4CATG4DGABARAPLOC717813 (ATG4B)
Protein Transport
ATG16L1ATG16L2ATG3ATG4AATG4CATG4DATG7ATG9AGABARAPGABARAPL2LOC711835 (ATG10)LOC717813 (ATG4B)RAB24
Autophagosome-Lysosome Linkage
DRAM1GABARAPNPC1
Ubiquitination
ATG7ATG3PARK7
Proteases
ATG4AATG4CATG4DLOC717813 (ATG4B)
Regulation of Autophagy
Co-Regulators of Autophagy & Apoptosis
AKT1APPATG5BCL2L1 (BCL-X)BADBAK1BAXBECN1CASP3CASP8 (FLICE)CDKN1BCLN3CTSBCXCR4DAPDAPK1DRAM1EIF2AK3FAS (TNFRSF6)IFNGIGF1LOC100426120 (BNIP3)LOC694767 (HDAC1)ATG12 (ATG12)BCL2 (BCL2)LOC708606 (FADD)HDAC6MAPK8 (JNK1)NFKB1PIK3CGPRKAA1 (AMPK)PTENSNCASQSTM1TGFB1TGM2TNFTNFSF10 (TRAIL)TP53 (p53)
Co-Regulators of Autophagy & the Cell Cycle
BAXCDKN1BIFNGMAPTPTENRB1TGFB1TP53 (p53)
Autophagy Induction by Intracellular Pathogens
EIF2AK3IFNGTLR9
Autophagy in Response to Other Intracellular Signals
EIF4G1ESR1 (ERα)GAAHGSCTSS (CTSS)LOC718976 (MAPK14, p38ALPHA)LOC718976 (MAPK14, p38ALPHA)PIK3CBPIK3C3PIK3R4RPS6KB1TMEM74ULK2UVRAG
Chaperone-Mediated Autophagy
LOC695913 (HSP90AA1)