Target List
Skeletal Muscle Contractility
Dystrophin-Glycoprotein Complex
CAMK2GCAPN3CAV3DAG1DMD (Dystrophin)DYSFEMDLMNAMAPK1 (ERK2)SGCA
Titin Complex
ACTA1ACTN3CAPN3CRYABDESLMNATTNLOC704095 (TNNT3)LOC721041 (TNNI2)MAPK1 (ERK2)MSTN (GDF8)MYH1MYH2MYOTNEBSGCATNNT1TRIM63 (MuRF1)
Energy Metabolism
HK2LOC709604 (CS)PDK4SLC2A4 (GLUT4)
Fast-Twitch Fibers
ATP2A1LOC721041 (TNNI2)LOC704095 (TNNT3)MYH1MYH2
Slow-Twitch Fibers
LOC697047 (TNNC1)MBMYH1TNNT1
Other Skeletal Muscle Contractility Genes
DMPKIKBKB (IKKβ)RPS6KB1
Skeletal Myogenesis
ACTA1ADRB2AGRNBMP4CAPN2CASTCAV1CTNNB1DMD (Dystrophin)HDAC5IGF1IGFBP3IGFBP5LOC702013 (PAX7)RHOA (RHOA)MBNL1MEF2CMSTN (GDF8)MUSKMYF5MYF6MYOD1MYOGPAX3PPP3CARPS6KB1UTRN
Skeletal Muscle Hypertrophy
ACTA1ACVR2BADRB2IGF1IGFBP5MSTN (GDF8)MYF6MYOD1RPS6KB1
Skeletal Muscle Autocrine Signaling
ADIPOQFGF2IGF1IL6LEPMSTN (GDF8)TGFB1
Diabetes / Metabolic Syndrome
ADIPOQLEPLOC711027 (PPARGC1B, PGC-1β)PPARGPPARGC1A (PGC-1α)PRKAA1 (AMPK)PRKAB2PRKAG1PRKAG3SLC2A4 (GLUT4)
Skeletal Muscle Wasting / Atrophy
Autophagy
CAPN2CASP3FBXO32 (Atrogin-1)FOXO1FOXO3LOC711027 (PPARGC1B, PGC-1β)MSTN (GDF8)NOS2 (iNOS)PPARGC1A (PGC-1α)RPS6KB1TRIM63 (MuRF1)
Dystrophy
AKT1AKT2FBXO32 (Atrogin-1)IL1BLOC718976 (MAPK14, p38ALPHA)LOC718976 (MAPK14, p38ALPHA)MAPK1 (ERK2)MAPK3 (ERK1)MAPK8 (JNK1)MMP9NFKB1TNFTRIM63 (MuRF1)UTRN