Target List
Induction of Apoptosis
Death Domain Receptors
TNFTNFRSF11BTNFRSF1ATNFRSF1B
DNA Damage & Repair
ABL1CIDEACIDEBTP53 (p53)
Extracellular Apoptotic Signals
LOC100516103
Other Pro-Apoptotic Genes
AIFM3BADBAK1BAXBIDBNIP3LCASP1CASP10CASP14CASP2CASP3LOC100522887CASP6CASP8 (FLICE)CD40CD70 (TNFRSF7)CYCSCUL2DFFADDX20DPF2DIABLOERN2FAS (TNFRSF6)FASLG (TNFSF6)FEM1BGADD45AHRKLTA (TNFB)LTBRLALBANOD1LOC100522011PPP2R1APPP2R1BSART1LOC100517325TNFSF10 (TRAIL)TP53BP2TRAF2
Anti-Apoptotic
AKT1BAG3BAXBCL2BCL2A1BCL2L1 (BCL-X, BCLXL)BCL2L10LOC100154044BRAFLOC100622859BIRC3BIRC5BNIP2BNIP3LCBX4BNIP3CD40LG (TNFSF5)CFDP1LOC100516103ERC1FAS (TNFRSF6)HRKIGF1RIL10MCL1MTL5NFKB1LOC100523672RIPK2PAK7STAMBPTNFXIAP
Death Domain Receptors
LOC100516103TNFRSF21TNFRSF11BTNFRSF1ATNFRSF1B
Caspases & Regulators
Caspases
CASP1CASP10CASP14CASP2CASP3LOC100522887CASP6CASP8 (FLICE)LOC100156777 (CASP7)CASP9LOC641352 (Caspase 15)LOC100522011
Caspase Activation
AIFM1AIFM3APAF1BAXBCL2L10CASP1NOD1LOC100522011TP53 (p53)
Caspase Inhibition
XIAP
Other Regulators of Apoptosis
PROP1RFWD2