Target List
HIF1 & Co-Transcription Factors
ARNTCOPS5HIF1AHIF3AHNF4ANCOA1PER1
Other HIF1 Interactors
APEX1EGLN1EGLN2NFKB1P4HA1TP53 (p53)
Hypoxia Responsive Genes
Angiogenesis
ADORA2BANGPTL4ANXA2BTG1EGR1EDN1EPOF3GPIHMOX1JMJD6LOXMMP9PGFPLAU (uPA)SERPINE1 (PAI-1)VEGFA
Coagulation
ALDOCANXA2F10F3PLAU (uPA)SERPINE1 (PAI-1)SLC16A3
DNA Damage & Repair
ATRMIFNDRG1RUVBL2
Metabolism
ALDOCDDIT4 (REDD1)ENO1ERO1AGBE1GPIGYS1HK2LDHAPDK1PFKFB3PFKFB4PFKLPFKPPGAM1PGK1PKMSLC2A1SLC2A3TPI1
Regulation of Apoptosis
ADMBNIP3BNIP3LBTG1DDIT4 (REDD1)IER3MIFNOS3 (eNOS)PIM1
Regulation of Cell Proliferation
ADMBTG1BLMCCNG2EGR1IGFBP3LOC100154269 (MXI1)METMIFNAMPTNOS3 (eNOS)ODC1PGFPIM1TXNIP
Transcription Factors
BHLHE40 (DEC1)FOSRBPJUSF2
Transporters, Channels & Receptors
SLC2A1SLC2A2SLC2A3SLC16A3TFRCVDAC1
Other Hypoxia Responsive Genes
ANKRD37CA9CTSADNAJC5EIF4EBP1 (4E-BP1)FAM162ALGALS3MAP3K1 (MEKK1)