Target List
Antioxidants
Glutathione Peroxidases (GPx)
GPX1, GPX2, GPX3, GPX4, GPX5, LOC100739163, GSTZ1
Peroxiredoxins (TPx)
PRDX1, PRDX2, PRDX3, PRDX4, PRDX5, PRDX6
Other Peroxidases
CAT, GP91-PHOX (CYBB), CYGB, DUOX1, DUOX2, EPX, LOC100516395 (LPO), MGST3, MPO, PTGS1, PTGS2 (PGHS-2, COX2), TTN, TTNLOC100620261 (TTN)
Other Antioxidants
ALB, APOE, GSR (GSR), MT-III (MT3), SOD1, SOD3, TXNRD1, TXNRD2, VIMP
Reactive Oxygen Species (ROS) Metabolism
Superoxide Dismutases (SOD)
SOD1, SOD3
Other Superoxide Metabolism Genes
ALOX12, DUOX1, DUOX2, MT-III (MT3), NCF1, NCF2, NOS2, NOX4, NOX5, UCP2
Other Reactive Oxygen Species (ROS) Metabolism Genes
AOX1, BNIP3, EPHX2, MPV17, SFTPD
Oxidative Stress Responsive Genes
APOE, CAT, CCL5 (RANTES), CYGB, DHCR24, DUOX1, DUOX2, DUSP1, EPX, FOXM1, FTH1, GCLC, GCLM, GPX1, GPX2, GPX3, GPX4, GPX5, GSR (GSR), GSS, HMOX1, HSP70.2 (HSPA1A), KRT1, LOC100516395 (LPO), MBL2, MPO, MSRA, NQO1, NUDT1, OXR1, OXSR1, PDLIM1, PRDX2, PRDX5, PRDX6, PRNP, RNF7, SCARA3, SEPP1, SIRT2, SOD1, SQSTM1, TTN, TTNLOC100620261 (TTN), TXN, TXNRD1, TXNRD2, VIMP
Oxygen Transporters
CYGB, MB
Pathway Activity Signature Genes
BAG2, FHL2, GCLM, GLA, HMOX1, HSP90AA1, LHPP, LOC100049683 (SLC7A11), LOC100622575 (SPINK1), LOC733635 (AKR1C2), NCOA7, NQO1, PTGR1, TRAPPC6B, TXN, TXNRD1