GeneGlobe ID: PASS-098Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Pig mTOR Signaling

RT2 Profiler PCR Array
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Product Specification

Target List
mTOR Complexes
mTORC1 Complex​
MLST8 (GBL), MTOR, RPTOR
mTORC2 Complex​
MLST8 (GBL), MTOR, RICTOR
mTOR Upstream Regulators
mTORC1 Positive Regulation​
AKT1, AKT2, AKT3, IGF1, IKBKB, INS, INSR, IRS1, KRAS, MAPK1 (ERK2), MAPK1 (ERK2), MAPK3 (ERK1), MAPK3 (ERK1), NRAS, PDPK1, PIK3C3 (VPS34), PIK3CA (p110-alpha), LOC100622663 (PIK3CB), PIK3CD, PIK3CG, PIK3R2 (p85-BETA), PLD1, PLD2, RHEB, RPS6KA1, RPS6KA2, RPS6KA4, LOC100152046, RRAGA, RRAGC, RRAGD, TELO2
mTORC2 Positive Regulation​
AKT1, AKT2, AKT3, MAPK1 (ERK2), MAPK1 (ERK2), MAPK3 (ERK1), MAPK3 (ERK1), PDPK1, PIK3C3 (VPS34), PIK3CA (p110-alpha), LOC100622663 (PIK3CB), PIK3CD, PIK3CG, PIK3R2 (p85-BETA), RHEB, RPS6KA1, RPS6KA2, RPS6KA4, LOC100152046
mTORC1 Negative Regulation​
AKT1S1, CAB39, CAB39L, DDIT4 (REDD1), DDIT4L (REDD2), DEPTOR (DEPDC6), FKBP1A, FKBP8, IGFBP3, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, LOC100738310, PTEN, STK11 (LKB1), STRADB, TP53 (p53), TSC1, TSC2, YWHAQ (14-3-3θ)
mTORC2 Negative Regulation​
CAB39, CAB39L, DDIT4 (REDD1), DDIT4L (REDD2), DEPTOR (DEPDC6), PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, LOC100738310, STK11 (LKB1), STRADB, TSC1, TSC2
mTOR Downstream Effectors
mTORC1 Positive Regulation​
CHUK (IKKα), EIF4E, HIF1A, IKBKB, RPS6, RPS6KB1, RPS6KB2, TP53 (p53), VEGFA, VEGFB, VEGFC (VEGFC)
mTORC2 Positive Regulation​
AKT1, CDC42, GSK3B, HSPA4 (HSP70), ILK, MYO1C, PRKCA, PRKCB, PRKCE, PRKCG, RHOA, RPS6KB1, SGK1
mTORC1 Negative Regulation​
EIF4EBP1 (4E-BP1), EIF4EBP2, PPP2CA, PPP2R2B, PPP2R4, TP53 (p53), ULK1, ULK2
Cellular Processes
Amino Acid Response​
PIK3C3 (VPS34), RRAGA, RRAGC, RRAGD
Angiogenesis​
CHUK (IKKα), DDIT4 (REDD1), DDIT4L (REDD2), HIF1A, IKBKB, VEGFA, VEGFB, VEGFC (VEGFC)
Autophagy​
PIK3C3 (VPS34), ULK1, ULK2
Cytoskeletal Organization​
CDC42, PRKCA, PRKCB, PRKCE, PRKCG, RHOA
Growth Factor Response​
BRAF, IGF1, IGFBP3, KRAS, MAPK1 (ERK2), MAPK1 (ERK2), MAPK3 (ERK1), MAPK3 (ERK1), NRAS, RPS6KA1, RPS6KA2, RPS6KA4, LOC100152046
Energy Stress​
PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, LOC100738310
Insulin Signaling​
AKT1, AKT2, AKT3, INS, INSR, IRS1, PDPK1, PIK3CA (p110-alpha), LOC100622663 (PIK3CB), PIK3CD, PIK3CG, PIK3R2 (p85-BETA), TP53 (p53)
Lipid Metabolism​
BRAF, PLD1, PLD2
Translation​
EIF4E, EIF4EBP1 (4E-BP1), EIF4EBP2, PPP2CA, PPP2R2B, PPP2R4, RPS6, RPS6KA1, RPS6KA2, RPS6KA4, LOC100152046, RPS6KB1, RPS6KB2
Gene Resource List
Array Layout for PCR Plates
File Size: 139.41 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 133.44 KBLanguage: English

Resources

Brochures & Guides (3)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Safety Data Sheets (1)
Download Files (3)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Poster for download
Kit Handbooks (1)
For pathway-focused gene expression profiling using real-time RT-PCR
Instrument Technical Documents (2)
For gene expression and genomic analysis
For pathway-focused gene expression analysis
Certificates of Analysis (1)
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