Target List
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents​
COL14A1, LOC397571, COL1A2, COL3A1, LOC397502, COL5A2, COL5A3, DCN, EDN1, VTN
Extracellular Matrix (ECM) Remodeling Enzymes​
CTSK, LOC100153504, LOC100514666, LOC100154047, PLAUR, F3, MMP1, MMP2, MMP3, MMP7, MMP9, PLAT (tPA), PLAU (uPA), PLG, SERPINE1 (PAI-1)
Cell Adhesion Molecules​
CDH1 (E-cadherin), ITGA2, LOC100517053, ITGA4, ITGA5, ITGA6, ITGAV, ITGB1, ITGB3, ITGB5, ITGB6, TNC
Cytoskeleton Regulators​
ACTA2 (ACT-4), ACTC1, RAC1, TAGLN
Inflammatory Cytokines & Chemokines
CCL2 (MCP-1), CD40LG (TNFSF5), CXCL11 (I-TAC, IP-9), CXCL12 (SDF1), LOC396594, IFNG, IL1A, IL10, IL1B, IL2, IL4
Growth Factors
ANGPT1, CTGF, CSF2 (GM-CSF), CSF3 (GCSF), EGF, FGF2, FGF7, HBEGF (DTR), IGF1, FGF10, MIF, TGFA, TGFB1, TNF, VEGFA
Signal Transduction
TGFβ / BMP Signaling​
SMAD3 (MADH3), TGFB1, TGFB2, TGFB3, TGFBR3
WNT Signaling​
CTNNB1, LOC100627044 (WISP1), WNT5A
Kinases​
AKT1, EPHB2, MET, MYLK, PTEN
Cell Surface Receptors​
EGFR (ERBB1), EPHB2, IL6ST (GP130), MET, TGFBR3
Other Signal Transduction Genes​
PTGS2 (PGHS-2, COX2), PTGS1, STAT3