Target List
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents
COL14A1, LOC397571, COL1A2, COL3A1, LOC397502, COL5A2, COL5A3, DCN, EDN1, VTN
Extracellular Matrix (ECM) Remodeling Enzymes
CTSK, LOC100153504, LOC100514666, LOC100154047, PLAUR, F3, MMP1, MMP2, MMP3, MMP7, MMP9, PLAT (tPA), PLAU (uPA), PLG, SERPINE1 (PAI-1)
Cell Adhesion Molecules
CDH1 (E-cadherin), ITGA2, LOC100517053, ITGA4, ITGA5, ITGA6, ITGAV, ITGB1, ITGB3, ITGB5, ITGB6, TNC
Cytoskeleton Regulators
ACTA2 (ACT-4), ACTC1, RAC1, TAGLN
Inflammatory Cytokines & Chemokines
CCL2 (MCP-1), CD40LG (TNFSF5), CXCL11 (I-TAC, IP-9), CXCL12 (SDF1), LOC396594, IFNG, IL1A, IL10, IL1B, IL2, IL4
Growth Factors
ANGPT1, CTGF, CSF2 (GM-CSF), CSF3 (GCSF), EGF, FGF2, FGF7, HBEGF (DTR), IGF1, FGF10, MIF, TGFA, TGFB1, TNF, VEGFA
Signal Transduction
TGFβ / BMP Signaling
SMAD3 (MADH3), TGFB1, TGFB2, TGFB3, TGFBR3
WNT Signaling
CTNNB1, LOC100627044 (WISP1), WNT5A
Kinases
AKT1, EPHB2, MET, MYLK, PTEN
Cell Surface Receptors
EGFR (ERBB1), EPHB2, IL6ST (GP130), MET, TGFBR3
Other Signal Transduction Genes
PTGS2 (PGHS-2, COX2), PTGS1, STAT3